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We've got another exciting Big Ten matchup on the schedule as the Northwestern Wildcats and the Indiana Hoosiers are set to tip at 3 p.m. ET on Sunday at Simon Skjodt Assembly Hall. Indiana is 14-10 overall and 10-3 at home, while Northwestern is 17-8 overall and 2-6 on the road. The Wildcats have won four of the last five meetings between these teams. 

This time around, Indiana is favored by 2 points in the latest Indiana vs. Northwestern odds, and the over/under is 137.5 points. Before entering any Northwestern vs. Indiana picks, you'll want to see the NCAA Basketball predictions from the proven computer model at SportsLine.

The model simulates every Division I college basketball game 10,000 times. It enters Week 15 of the 2023-24 season on a 131-88 roll on all top-rated college basketball picks dating back to last season, returning nearly $2,500 for $100 players. It is also off to a sizzling 24-12 start on top-rated spread picks this season. Anyone following has seen huge returns.

The model has set its sights on Northwestern vs. Indiana. You can head to SportsLine to see its picks. Here are several college basketball betting lines for the game:

  • Indiana vs. Northwestern spread: Indiana -2
  • Indiana vs. Northwestern over/under: 137.5 points
  • Indiana vs. Northwestern money line: Indiana: -133, Northwestern: +113
  • Indiana vs. Northwestern picks: See picks here

What you need to know about Northwestern

Northwestern suffered its closest loss since December 13, 2023, on Thursday. The Wildcats fell just short of the Scarlet Knights by a score of 63-60. Northwestern got off to an early lead (up 13 with 5:21 left in the first quarter), but sadly the Wildcats weren't able to maintain that momentum.

Northwestern's loss came about despite a quality game from Boo Buie, who went 6 for 10 from beyond the arc en route to 27 points. For the season, Buie is averaging 19.2 points, 5.2 assists, and 3.6 rebounds. 

What you need to know about Indiana

The Hoosiers suffered a serious setback last Saturday. They suffered a painful 79-59 loss at the hands of the Purdue Boilermakers. The loss doesn't tell the whole story though, as several players had good games. One of the most active was CJ Gunn, who scored 13 points. 

The Hoosiers also got some help courtesy of Kel'el Ware, who scored 11 points to go along with eight rebounds. Indiana is 16-4 in its last 20 games at home, but the Hoosiers enter Sunday's showdown having lost five of their last seven games overall. 

How to make Indiana vs. Northwestern picks

The model has simulated Indiana vs. Northwestern 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins Northwestern vs. Indiana, and which side of the spread hits well over 50% of the time? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that is on a 131-88 roll on its top-ranked college basketball picks, and find out.