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The Colorado Buffaloes (3-2) will try to snap their first losing streak of the Deion Sanders era when they go on the road for a meeting with the Arizona State Sun Devils (1-4) on Saturday. Colorado won its first three games of the season before losing consecutive games to top-10 opponents in Oregon and USC. The Buffaloes scored the final 20 points of the game in their 48-41 loss against No. 8 USC last week. Arizona State is riding a four-game losing streak, falling to California in its most recent contest.

Kickoff is set for 6:30 p.m. ET on Saturday at Mountain America Stadium in Tempe. Colorado is favored by 3 points in the latest Colorado vs. Arizona State odds, while the over/under is set at 58.5 points, per SportsLine consensus. Before entering any Colorado vs. Arizona State picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of more than $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

The model has set its sights on Colorado vs. Arizona State. You can head to SportsLine to see its picks. Here are several college football betting lines for the Arizona State vs. Colorado game:

  • Colorado vs. Arizona State spread: Colorado -3
  • Colorado vs. Arizona State over/under: 58.5 points
  • Colorado vs. Arizona State money line: Arizona State +134, Colorado -159
  • Colorado vs. Arizona State picks: See picks here
  • Colorado vs. Arizona State live stream: fubo (try for free)

Why Arizona State can cover

Colorado was seemingly on its way to a second straight blowout loss last week, but USC let off the gas and made the final score much closer than it was earlier in the game. The Buffaloes failed to cover the spread in their previous two games, suggesting that the betting market has made an appropriate adjustment following their hot start. Meanwhile, Arizona State has covered the spread in back-to-back games, playing close contests as a double-digit underdog against USC and California.

The Sun Devils were 13-point underdogs in their 24-21 loss to the Golden Bears last week, as their comeback effort came up just short. Junior quarterback Trenton Bourguet completed 26 of 41 passes for 344 yards in his first start of the season, and he is expected to get another opportunity this weekend. Colorado's defense has allowed at least 35 points in four of its first five games, giving Arizona State a clear path to victory on Saturday night.

Why Colorado can cover

Colorado is coming off consecutive losses to Oregon and USC, but it opened the season with three straight wins and will be taking a step down in competition this weekend. The Buffaloes cruised to a blowout win over Nebraska while notching victories over then-No. 17 TCU and Colorado State before losing to a pair of top-10 teams. Despite their loss to USC, they were able to generate some momentum by scoring the final 20 points of the game.

Junior quarterback Shedeur Sanders has thrown for 1,781 yards and 15 touchdowns, going over 340 passing yards in four of his five outings. He added 50 rushing yards and a rushing touchdown against USC, so he will be difficult for Arizona State to slow down. The Sun Devils have lost eight of their last nine games, including six straight against Pac-12 opponents. See which team to pick here. 

How to make Arizona State vs. Colorado picks

The model has simulated Colorado vs. Arizona State 10,000 times and the results are in. The model is leaning Over, and it's also generated a point-spread pick that is hitting in 70% of simulations. You can only see the pick at SportsLine.

So who wins Arizona State vs. Colorado, and which side of the spread hits 70% of the time? Visit SportsLine now to see which side of the Colorado vs. Arizona State spread to jump on, all from the advanced computer model that's up more than $2,000 on its top-rated college football spread picks since its inception, and find out.