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No. 23 UCLA (5-2) will be seeking consistency when it hosts Colorado (4-3) on Saturday night. The Bruins have alternated between wins and losses in five straight games, with their most recent outing being a 42-7 blowout win at Stanford last week. Colorado had the week off following its double-overtime loss to Stanford two weeks ago, as the Buffaloes blew a 29-point lead in the stunning setback. UCLA is in sixth place in the Pac-12 standings, while Colorado is in eighth.

Kickoff is set for 7:30 p.m. ET at the Rose Bowl. The Bruins are 15-point favorites in the latest UCLA vs. Colorado odds from SportsLine consensus. The over/under is 60, down four points from the opening line. Before making any Colorado vs. UCLA picks, be sure to check out the college football predictions and betting advice from SportsLine football expert Jimmie Kaylor

Kaylor is a NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. As a Colorado native, he has his finger on the pulse of the local and national sports scene and has been cashing big on Denver area teams for the last two years. 

Kaylor has been red-hot on his Colorado picks this season, going 15-6 on his best bets in the Buffs' first seven games, including a 5-1 mark in the CU vs. USC game. He's also 33-12-2 on all of his CFB best bets this season so far. Anyone who has followed his picks is way up.

Now, he has set his sights on Colorado vs. UCLA and just locked in its picks and CFB predictions. You can head to SportsLine now to see Kaylor's picks. Here are several college football odds and betting lines for UCLA vs. Colorado:

  • Colorado vs. UCLA spread: UCLA -15
  • Colorado vs. UCLA over/under: 60 points
  • Colorado vs. UCLA money line: Colorado +478, UCLA -695
  • CU: WR Xavier Weaver has 50 catches for 631 yards and 4 TDs.
  • UCLA: LB Laiatu Latu has 6.5 sacks.
  • Colorado vs. UCLA picks: See picks at SportsLine
  • Colorado vs. UCLA live stream: fubo (try for free)

Why Colorado can cover

Colorado's bye week came at the perfect time, as it gave the Buffaloes a chance to reset following their heartbreaking loss to Stanford. They held a 29-point lead before everything unraveled, keeping them from winning back-to-back games for the third time this season. Quarterback Shedeur Sanders leads one of the nation's premier offenses, racking up 2,420 passing yards, 21 touchdowns and three interceptions.

Two-way star Travis Hunter returned after missing a month due to a lacerated liver, catching 13 passes for 140 yards and two touchdowns against Stanford. UCLA quarterback Dante Moore has been dealing with an injury, so head coach Chip Kelly has not named a starter for this game. The Bruins have only covered the spread twice in their last seven conference games, and Colorado presents a unique challenge under first-year coach Deion Sanders. See which team to pick at SportsLine

Why UCLA can cover

The Bruins enter this matchup as one of college football's top teams on both sides of the ball. Offensively, the Bruins are averaging 464.4 total yards per game, which ranks 17th in the country. Their rushing attack, behind the running back duo of Carson Steele and TJ Harden, ranks ninth in college football, averaging 215.6 yards per game. Steele enters this matchup with 599 yards and six touchdowns, while Harden has 388 yards and four TDs.

Defensively, the Bruins rank second in rushing defense (68.6 yards per game) and 10th in points allowed per game (14.9). UCLA has 24 total sacks in 2023, and their pass rush, led by linebacker Laiatu Latu (6.5 sacks), could have a field day against Colorado's below average offensive line. See which team to back at SportsLine

How to make UCLA vs. Colorado picks

Kaylor has analyzed this matchup from every angle and he's going Under on the point total. He has also discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing what it is, and which side to back, at SportsLine.

Who wins Colorado vs. UCLA, and which critical X-factor makes one side of the spread a must-back? Visit SportsLine now to see Colorado vs. UCLA picks, all from the expert who has covered college football for over a decade and is 15-6 on his Colorado best bets in 2023, and find out.