The No. 20 Kansas State Wildcats have a chance to remain unbeaten in conference play when they face the Iowa State Cyclones in a road game on Saturday night. Kansas State has won consecutive games since suffering a shocking loss to Tulane in mid-September. Iowa State is looking to snap a two-game losing skid after dropping a 14-11 final to unbeaten Kansas last week.

Kickoff is set for 7:30 p.m. ET. The Wildcats are 1-point favorites in the latest Kansas State vs. Iowa State odds from Caesars Sportsbook, while the over/under for total points scored is 45. Before entering any Iowa State vs. Kansas State picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Iowa State vs. Kansas State and just locked in its CFB picks and predictions. You can head to SportsLine to see its picks. Here are several college football odds and betting lines for Iowa State vs. Kansas State:

  • Iowa State vs. Kansas State spread: Kansas State -1
  • Iowa State vs. Kansas State over/under: 45 points
  • Iowa State vs. Kansas State picks: See picks here
Featured Game | Iowa State Cyclones vs. Kansas State Wildcats

What you need to know about Iowa State

Iowa State fell 14-11 to the Kansas Jayhawks last timeout. Quarterback Hunter Dekkers struggled in the loss as he turned the ball over twice (one interception and one fumble). However, the Iowa State defense was able to hold a high-powered Kansas offense to just 213 yards on the day.

The Jayhawks had been averaging 474 yards of total offense and 48.5 points per game in their four prior contests. O'Rien Vance had six tackles, a tackle for loss, a forced fumble and a fumble recovery in the win. Vance leads the team in tackles (28), tackles for loss (4.5) and forced fumbles (3) this season and he'll need to be a disruptive force against a run-heavy Kansas State attack.

What you need to know about Kansas State

Kansas State has multiple key factors on its side heading into this game, with one of them being recent form. The Wildcats pulled off a 41-34 upset at then-No. 6 Oklahoma two weeks ago as 13.5-point underdogs before taking care of business in a 37-28 win over Texas Tech last week. They have won and covered the spread in five of their last six games dating back to the end of last season.

Iowa State is trending in the opposite direction following back-to-back losses against then-No. 17 Baylor and Kansas, despite being favored in both games. The Cyclones have covered the spread four times in their last 12 games, and they are averaging just 15 points per game during conference play. Their lack of offense is going to make it difficult for them to keep pace with Kansas State quarterback Adrian Martinez, who has already gone over 1,000 total yards this season. 

How to make Kansas State vs. Iowa State picks

The model has simulated Iowa State vs. Kansas State 10,000 times and the results are in. Th model is leaning Over on the total and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the model's pick at SportsLine.

Who will win Iowa State vs. Kansas State? And which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread you need to jump on Saturday, all from the model that has crushed its college football picks, and find out.