The Vanderbilt Commodores and the Tennessee Volunteers will face off in an SEC East clash at 3:45 p.m. ET on Saturday at Neyland Stadium. Tennessee is 6-5 overall and 4-3 at home, while the Commodores are 2-9 overall and 1-3 on the road. It's the 116th time the in-state rivals have met and Tennessee has a massive 77-33-5 edge in the all-time series. Vanderbilt, however, has won five of the last nine.

Vanderbilt has also covered in seven of the last 10 head-to-head meetings, though it was Tennessee who won and covered as a 15-point favorite last season. This time around, the Volunteers are favored by 31.5 points in the latest Tennessee vs. Vanderbilt odds from Caesars Sportsbook, and the over-under is set at 63.5. Before entering any Vanderbilt vs. Tennessee picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 12 of the 2021 season on a 36-23 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Tennessee vs. Vanderbilt. You can head to SportsLine to see its picks. Here are several college football odds for Vanderbilt vs. Tennessee:

  • Tennessee vs. Vanderbilt spread: Tennessee -31.5
  • Tennessee vs. Vanderbilt over-under: 63.5 points
Featured Game | Tennessee Volunteers vs. Vanderbilt Commodores

What you need to know about Tennessee

The Volunteers were completely in charge against South Alabama last week, breezing past the Jaguars 60-14 at home. Tennessee quarterback Hendon Hooker passed for two touchdowns and 273 yards on 20 attempts in addition to punching in one rushing touchdown.

Hooker and the Tennessee offense have been among the biggest surprises in the SEC this season. The Virginia Tech transfer has completed 70.0 percent of his passes since taking over as the starter and has thrown for 2,411 yards and 24 touchdowns with just three interceptions, while rushing for 485 yards and five scores as well. The Volunteers rank 11th nationally in scoring offense as they average 38.3 points per game.

What you need to know about Vanderbilt

Meanwhile, the Commodores came up short against the Ole Miss Rebels on Saturday, falling 31-17. Running back Rocko Griffin Jr. put forth a good effort for the losing side as he rushed for one touchdown and 117 yards on 26 carries. It was Griffin's second 100-yard rushing game of the season.

Vanderbilt put up a season-high 454 yards of total offense against a top-10 team in the country in the loss, so it was a sign of progress for Clark Lea's squad during a tough first season as head coach. However, Lea's defense will be challenged by Tennessee talent and tempo after surrendering at least 400 yards in 10 consecutive games.

How to make Tennessee vs. Vanderbilt picks

The model is leaning under on the total and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Vanderbilt vs. Tennessee? And which side of the spread hits over 60 percent of the time? Visit SportsLine now to see which side of the spread you need to be all over, all from the model that has crushed its college football picks, and find out.