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An ACC battle is on tap between the Duke Blue Devils and the Wake Forest Demon Deacons at 4 p.m. ET on Saturday at Truist Field. Wake Forest, the leader in the ACC Atlantic Division, is 7-0 overall and 4-0 at home, while Duke is 3-4 overall and 0-3 on the road. The Blue Devils have lost three straight entering this matchup. Wake Forest, meanwhile, is up to No. 13 in the AP Poll as it continues to pile up points at an eye-popping rate. 

The Demon Deacons are favored by 16.5 points in the latest Wake Forest vs. Duke odds from Caesars Sportsbook. The over-under for total points is set at 69. Before entering any Duke vs. Wake Forest picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,900 for $100 players on its top-rated college football picks against the spread. It also enters Week 9 of the 2021 season on a 26-11 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Wake Forest vs. Duke. You can head to SportsLine to see its picks. Here are several college football odds for Duke vs. Wake Forest:

  • Wake Forest vs. Duke spread: Wake Forest -16.5
  • Wake Forest vs. Duke over-under: 69 points

What you need to know about Wake Forest

Army is typically tough to beat at home, but last Saturday the Demon Deacons proved too difficult a challenge. Wake Forest walked away with a 70-56 victory. Quarterback Sam Hartman passed for five TDs and 458 yards on 29 attempts, in addition to punching in one rushing touchdown. Hartman's 75-yard touchdown toss to receiver Jaquarii Roberson in the third quarter made for one of the most memorable moments of the day. 

Wake Forest ranks 13th nationally in scoring offense with 43.1 points per game. The Demon Deacons do most of their damage through the air, ranking 16th nationally with 297.3 passing yards per game. But Dave Clawson's squad has balance too, averaging 172.1 rushing yards per game. 

What you need to know about Duke

Meanwhile, Duke fell 48-0 to the Virginia Cavaliers in its last outing The Blue Devils were in a tough position by the half, with the score already sitting at 34-0. Quarterback Gunnar Holmberg failed to produce a single touchdown. He also threw two interceptions with only 134 yards passing.

It was the third consecutive loss for Duke, but the Blue Devils have been respectable against the spread this season despite their overall struggles. They are 3-3 ATS against FBS competition, though they've yet to cover on the road this season. 

How to make Duke vs. Wake Forest picks

The model is leaning over on the total, and it's also generated a point-spread pick that is hitting in almost 70 percent of simulations. You can only see the pick at SportsLine.

So who wins Wake Forest vs. Duke? And which side of the spread hits almost 70 percent of the time? Visit SportsLine to see which side of the spread to back, all from the model that's crushed its college football picks