The American League Central-leading Minnesota Twins look to extend their road winning streak to five games when they visit the division-rival Detroit Tigers on Monday afternoon for the opener of their five-game series. Minnesota (29-19) has outscored its opponents 36-16 over its past four road contests and has recorded 20 runs in its last three overall outings after Sunday's 7-3 home victory against Kansas City. Detroit (17-29) has won five of six at home after edging Cleveland 2-1 on Sunday.

First pitch from Comerica Park is set for 1:10 p.m. ET. Minnesota is a -155 favorite (risk $155 to win $100) on the money line in the latest Twins vs. Tigers odds from Caesars Sportsbook, while the over-under for total runs scored is 8.5. Before making any Tigers vs. Twins picks, be sure to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It's on a 48-31 roll on top-rated MLB money-line picks through seven weeks, returning over $1,100 for $100 players. Anyone following it has seen huge returns.

Now, the model has set its sights on Twins vs. Tigers and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Tigers vs. Twins:

  • Twins vs. Tigers money line: Minnesota -155, Detroit +135
  • Twins vs. Tigers over-under: 8.5 runs
  • Twins vs. Tigers run line: Minnesota -1.5 (+105)
  • Twins vs. Tigers tickets: See tickets at StubHub
  • MIN: The Twins are 1-4 in their last five games at Detroit
  • DET: The Tigers are 1-5 in their last six contests as home underdogs
Featured Game | Detroit Tigers vs. Minnesota Twins

Why you should back the Twins

Minnesota displayed some early power in Sunday's victory as Gio Urshela hit a three-run homer in the third inning to open the scoring before Nick Gordon and Trevor Larnach began the fourth with back-to-back blasts. Urshela has hit safely in eight of his last nine games and has done well at the plate against the Tigers thus far this season, going 10-for-21 with three RBIs. Larnach has gone deep in two straight games and also has excelled versus Detroit as he is 6-for-14 with a homer and three RBIs in five contests, while Luis Arraez is riding a nine-game hitting streak during which he has posted seven multi-hit performances.

Another member of the Twins who has impressed against the Tigers this year is Mondays starter Dylan Bundy, who deserved a better outcome for his efforts. The 29-year-old right-handed made the start versus Detroit last Wednesday and settled for a no-decision despite giving up just one run and five hits over 5 ⅔ innings. After being tagged for nine runs and 11 hits in 3 ⅔ innings at Baltimore on May 4, Bundy has yielded one run and seven hits in 8 ⅔ frames over his last two outings.

Why you should back the Tigers

Detroit, who will start righty Beau Brieske, managed to record only four hits in Sunday's 2-1 home triumph against Cleveland, but two were solo home runs by Harold Castro and Jeimer Candelario. The duo also put on a power display in the Tigers' 4-2 victory at Minnesota last Wednesday, with Castro hitting a pair of solo shots and Candelario belting a decisive two-run homer in the 10th inning. The 28-year-old Castro is swinging a hot bat as he has gone 7-for-11 over his last three contests.

The Tigers have been playing well of late, winning three of their last four games after a stretch during which they lost five of six. They also have performed better at home, winning five of their last six contests at Comerica Park. Slugger Miguel Cabrera missed Sunday's game with lower back tightness but hopes to get back in the lineup as he has recorded three multi-hit efforts over his last five outings.

How to make Tigers vs. Twins picks

SportsLine's model is leaning over on the total, projecting 8.7 combined runs. It also says one side of the money line has all the value. You can only get the model's MLB picks at SportsLine.

So who wins Twins vs. Tigers? And which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.