Lavine Williams Bulls

The Detroit Pistons and the Chicago Bulls will face off in a Central Division clash at 7 p.m. ET on Wednesday at Little Caesars Arena. Chicago ended last season third in the Central Division at 31-41, while the Pistons finished fifth at 20-52. The Bulls have won the last seven meetings between the teams. 

Detroit finished with the worst record in the Eastern Conference last season. Chicago is favored by five-points in the latest Pistons vs. Bulls odds from Caesars Sportsbook, and the over-under is set at 218.5. Before entering any Bulls vs. Pistons picks, you'll want to see the NBA predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned almost $9,000 in profit on its top-rated NBA picks over the past three seasons. The model finished up almost $600 on its top-rated picks last season and enters the 2021-22 NBA season on a stunning 100-66 roll on top-rated NBA picks against the spread. Anyone following it has seen huge returns.

Now, the model has set its sights on Pistons vs. Bulls. You can head to SportsLine to see its picks. Here are several NBA betting lines for Pistons vs. Bulls:

  • Pistons vs. Bulls spread: Bulls -5
  • Pistons vs. Bulls over-under: 218.5 points
Featured Game | Detroit Pistons vs. Chicago Bulls

What you need to know about the Bulls

Lonzo Ball, who was acquired from New Orleans in August, and DeMar DeRozan, who also was acquired from San Antonio in the offseason, will both debut for Chicago on Wednesday. The Bulls won all four of their preseason games. Ball scored 19 points in the second exhibition game and DeRozan totaled 42 points on the final two preseason contests. 

Zach Lavine had two 30-point outings vs. Detroit last season, and averaged 27.4 points, 5.0 rebounds and 4.9 assists per game. The Bulls have a 29-26 record in season openers. 

What you need to know about the Pistons

Cade Cunningham, the No. 1 overall pick by the Pistons in the 2021 NBA Draft, has been ruled out for Wednesday's game with an ankle injury. It is uncertain when he will play in his first game. Killian Hayes has recovered from a concussion and is expected to be ready for the season opener. Kelly Olynyk, who was signed as a free agent in August, will play in his first game for the Pistons on Wednesday. 

The Pistons' bench averaged 41.3 points per game last season, best in the NBA. Saddiq Bey made a franchise rookie 175 3-pointers last year. Bey averaged 12.2 points, 4.5 rebounds and 1.4 assists per game last season. 

How to make Bulls vs. Pistons picks

The model has simulated Pistons vs. Bulls 10,000 times and the results are in. We can tell you that the model is leaning under, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Pistons vs. Bulls? And which side of the spread hits in over 60 percent of simulations? Visit SportsLine now to find out which side of the Pistons vs. Bulls spread you need to jump on Wednesday, all from the model that has crushed its NBA picks, and find out