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Eagles quarterback Jalen Hurts will try to build on a monster 2022 season when he faces New England on Sunday during the Week 1 NFL schedule. Hurts led Philadelphia to a Super Bowl appearance, earning a long-term deal this offseason after racking up 3,701 passing yards and 22 touchdowns. He also rushed for 760 yards and 13 scores, making him one of the most popular Week 1 NFL DFS picks. Hurts is facing a Patriots defense that ranked eighth in the league last year, allowing 322.0 yards per game in one of the friendliest NFL DFS matchups. While Hurts provides versatility in NFL DFS lineups, he is also one of the most expensive options in the Week 1 NFL DFS player pool on sites like DraftKings and FanDuel.

Should you include him in your Week 1 NFL DFS strategy? Before setting your NFL DFS lineups for Week 1 on sites like DraftKings and FanDuel, be sure to check out the NFL DFS advice, strategy and stacks from SportsLine daily Fantasy expert Mike McClure

McClure is a legendary professional DFS player with over $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings.

He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1 percent in more than a dozen other tournaments. Last year, he won the DraftKings Millionaire Maker twice and the FanDuel Million once.

Now, McClure has turned his attention to the Week 1 NFL schedule and locked in his top daily Fantasy football picks. You can only see them by heading to SportsLine.

Top NFL DFS picks for Week 1

One of McClure's top NFL DFS picks for Week 1 is Vikings receiver Justin Jefferson at $8,800 on DraftKings and $9,500 on FanDuel. The 2022 AP NFL Offensive Player of the Year is coming off a season in which he caught 128 passes for 1,809 yards and scored nine total touchdowns. He was the youngest player in NFL history to lead the league in receptions and receiving yards and is in uncharted waters over his first three seasons.

Jefferson's 324 receptions for 4,825 yards are both NFL records over a player's first three years and he has three games to become the fastest player in history to 5,000 receiving yards. He'll take on a Buccaneers defense that ranked 28th in passing touchdowns allowed (29) and Jefferson had nine games in which he produced at least 22 points on FanDuel and DraftKings last year.

Part of McClure's optimal NFL DFS strategy also includes rostering Dolphins receiver Tyreek Hill at $8,200 on DraftKings and $8,800 on FanDuel. Hill started off the 2022 season red-hot, garnering double-digit targets in three of his first four games and scoring twice during that stretch.

Hill had 119 targets last season and now faces the Chargers in a game with the second-highest over-under of the week. Chargers vs. Dolphins is the only NFL game on Sunday with a projected point total north of 50, giving Hill sky-high upside. See the rest of McClure's NFL DFS player pool here.

How to set NFL DFS lineups for Week 1

McClure is also targeting an undervalued player who is set to explode for huge numbers in Week 1. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is here

So who is Mike McClure putting in his optimal NFL DFS lineups for Week 1? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from a daily Fantasy expert with more than $2 million in winnings, and find out.