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The No. 6 Arizona Wildcats (12-1) host the Colorado Buffaloes (11-3) in a key Pac-12 matchup at 11 p.m. ET on Thursday, Jan. 13 at McKale Memorial Center in Tucson, Ariz.. Arizona is coming off a dominant 95-79 win over Washington on Jan. 3, while Colorado also knocked off the Huskies 78-64 in its last outing on Jan. 9. 

Arizona is favored by 16 points in the latest Arizona vs. Colorado odds from Caesars Sportsbook, and the over-under is set at 149.5. Before locking in any Colorado vs. Arizona picks, you need to see the college basketball predictions and betting advice from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Arizona vs. Colorado, and just locked in its picks and CBB predictions. You can head to SportsLine to see the model's CBB picks. Here are several college basketball odds and betting lines for Arizona vs. Colorado:

  • Arizona vs. Colorado spread: Arizona -16
  • Arizona vs. Colorado over-under: 150 points
  • Arizona vs. Colorado moneyline: Arizona -1700, Colorado +900

What you need to know about Arizona

The Wildcats strolled past the Washington Huskies with points to spare last Monday, taking the game 95-79. Four players on Arizona scored in the double digits: guard Bennedict Mathurin (27), center Christian Koloko (22), guard Kerr Kriisa (21), and guard Dalen Terry (13).

Mathurin has been dominant for the Wildcats in 2021-22, averaging 18.9 points, 6.5 rebounds, and 2.1 assists per game. The sophomore is well on his way to earning multiple postseason honors at his current pace. Arizona is 8-4-1 against the spread this season.

What you need to know about Colorado

Meanwhile, Colorado didn't have too much trouble with Washington at home on Sunday as they won 78-64. Forward Tristan da Silva filled up the stat sheet, picking up 22 points in addition to six boards.

The Buffs have won five straight games and eight of their last 10. Sophomore forward Jabari Walker leads the way for the Buffaloes, averaging 13.4 points, 8.4 rebounds, and 1.1 assists per game. Colorado is 4-8-2 against the spread this year.

How to make Colorado vs. Arizona picks

The model has simulated Arizona vs. Colorado 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it's also generated a point-spread pick that is hitting in almost 70 percent of simulations. You can only see the model's Arizona vs. Colorado pick at SportsLine.

So who wins Colorado vs. Arizona? And which side of the spread hits in almost 70 percent of simulations? Visit SportsLine now to see which side of the Arizona vs. Colorado spread to jump on, all from the advanced model that is up nearly $2,200 on its college basketball picks the last five years, and find out.