The No. 19 Kentucky Wildcats will host the No. 3 Louisville Cardinals at 3:45 p.m. ET on Saturday at Rupp Arena in an SEC vs. ACC battle that will be televised by CBS. Kentucky is 8-3 overall and 7-1 at home, while Louisville is 11-1 overall and 1-0 on the road. The Wildcats are favored by 1.5 points in the latest Kentucky vs. Louisville odds, and the over-under for total points is set at 131.5. Before entering any Louisville vs. Kentucky picks, you'll want to see the college basketball predictions from the model at SportsLine.

This model, which simulates every game 10,000 times, has crushed its top-rated college basketball picks against the spread the past three years, returning $2,770 to $100 players. Anybody who followed it during that span has seen huge returns.

Now, it has simulated Kentucky vs. Louisville 10,000 times and the results are in. We can tell you that the model is leaning over, and it's also generated a point-spread pick that is hitting in well over 60 percent of simulations. You can only see the pick at SportsLine.

The Wildcats were within striking distance but couldn't close the gap on Saturday as they fell 71-65 to Ohio State. That was their second consecutive loss after falling to Utah the prior game. Guard Ashton Hagans leads Kentucky with 13.9 points per game this season, while Tyrese Maxey is close behind with 13.1. The Wildcats are 4-7 against the spread this season and are 3-5 against the number at Rupp Arena. 

Louisville, who is 7-5 against the spread, has been one of the nation's best teams thus far with a loss against Texas Tech its only blemish. The Cardinals are coming off back-to-back comfortable victories over Eastern Kentucky and Miami (Ohio). Forward Jordan Nwora has been the catalyst for the Cardinals as he enters Saturday with 21.2 points and 7.5 rebounds per contest. A possible lottery pick in the 2020 NBA Draft, Nwora has hit the 20-point plateau in all but four games this year.

Statistically, these teams match up relatively close. Louisville averages 76.7 points per game, while Kentucky isn't far behind at 74.5. The Cardinals are slightly better on the defensive end, giving up just 58.4 points, with the Wildcats conceding 61.2. 

So who wins Kentucky vs. Louisville? And which side of the spread hits in well over 60 percent of simulations? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that has crushed its college picks