The Siena Saints and the Manhattan Jaspers are set to square off in an MAAC matchup at 7 p.m. ET Friday at Draddy Gymnasium. Manhattan is 9-5 overall and 4-2 at home, while the Saints are 6-6 overall and 4-3 on the road. Manhattan prevailed by an overtime score of 77-72 when these teams last played in December.

The Jaspers are favored by 2.5 points in the latest Manhattan vs. Siena odds from Caesars Sportsbook, and the over-under is set at 135. Before entering any Siena vs. Manhattan picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,400 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Manhattan vs. Siena. You can head to SportsLine to see its picks. Here are several college basketball odds for Siena vs. Manhattan:

  • Manhattan vs. Siena spread: Manhattan -2.5
  • Manhattan vs. Siena over-under: 135 points
Featured Game | Manhattan Jaspers vs. Siena Saints

What you need to know about Manhattan

The Jaspers came up short against the Niagara Purple Eagles on Tuesday, falling 72-63. Manhattan jumped out to a 33-24 first half lead but were then outscored by 18 points in the second half. Jose Perez and Warren Williams led the Jaspers with 16 points each and Williams came off the bench to knock down all eight of his field goal attempts.

Perez and Williams are two of three Jaspers averaging in double figures, along with senior guard Anthony Nelson. The Jaspers are an attack-the-rim team as they lead all of Division I in both free throw attempts and free throw makes. However, that comes to the detriment of their perimeter shooting as they rank 326th out of 358 Division I teams in made three-pointers.

What you need to know about Siena

Meanwhile, Siena was able to grind out a solid win over the Marist Red Foxes last Friday, winning 67-60. It was Siena's fourth win in a row as the school has gone undefeated since losing to Manhattan in early December. Siena overcame a 14-point halftime deficit as it outscored Marist 43-22 in the second half.

Colby Rogers led the Saints with 16 points off the bench as he didn't start for the first time this season. Rogers also leads the team in scoring this season with 13.7 points per game, including 44.1 percent from beyond the arc. Big man Jackson Stormo leads the Saints' efforts on the defensive end as he ranks sixth in the MAAC in both rebounds per game (7.1) and blocks per game (1.0).

How to make Siena vs. Manhattan picks

The model has simulated Manhattan vs. Siena 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Siena vs. Manhattan? And which side of the spread hits over 50 percent of the time? Visit SportsLine now to see which side of the Manhattan vs. Siena spread to jump on, all from the advanced model that is up over $2,400 on its college basketball picks the last five years, and find out.