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The No. 12 seed Notre Dame Fighting Irish and the No. 5 seed Wake Forest Demon Deacons battle in the second round of the 2024 ACC Tournament on Wednesday. Notre Dame leads the all-time series 9-8 over Notre Dame. On Feb. 27, the Fighting Irish defeated the Demon Deacons 70-65. 

Tipoff from Capital One Arena in Washington D.C. is set for 2:30 p.m. ET. The Demon Deacons are 9.5-point favorites in the latest Notre Dame vs. Wake Forest odds from SportsLine consensus, while the over/under for total points is 136.5. Before making any Wake Forest vs. Notre Dame picks, be sure to see the college basketball predictions and betting advice from the proven SportsLine Projection Model.

The model simulates every Division I college basketball game 10,000 times. It enters 2024 conference championship week on a 145-104 roll on all top-rated college basketball picks dating back to last season, returning more than $1,700 for $100 players. It also has a strong 28-18 (+820) record on top-rated spread picks this season. Anyone following has seen huge returns.

Now, the model has set its sights on Wake Forest vs. Notre Dame and revealed its CBB picks and predictions. You can head to SportsLine now to see the model's picks. Here are several college basketball odds and trends for Notre Dame vs. Wake Forest:

  • Notre Dame vs. Wake Forest spread: Demon Deacons -9.5
  • Notre Dame vs. Wake Forest over/under: 136.5 points
  • Notre Dame vs. Wake Forest money line: Demon Deacons -497, Fighting Irish +373
  • WAKE: Wake Forest has hit the team total Over in 20 of its last 28 games
  • ND: Notre Dame is 18-13 ATS this season
  • Notre Dame vs. Wake Forest picks: See picks at SportsLine

Why Wake Forest can cover

Junior guard Cameron Hildreth is a strong scorer for this squad. Hildreth operates well in the pick-and-roll as a scorer or facilitator. The native of England averages 13.5 points, 4.8 rebounds and 2.6 assists per game. He's scored 15-plus in two of his last four games. On Mar. 5 against Georgia Tech, Hildreth finished with 17 points and two boards.

Senior forward Andrew Carr gives the Demon Deacons a lengthy presence in the frontcourt. Carr scores in the low post and has a soft touch in the lane. The Pennsylvania native logs 13.3 points, 6.4 rebounds and shoots 52% from the field. In the season-finale win over Clemson, Carr had 17 points, five rebounds and three assists. See which team to pick here.

Why Notre Dame can cover

Freshman guard Markus Burton is a strong playmaker for the Irish. He is logging 17.3 points, 3.3 rebounds and 4.3 assists per game this season. In the first-round win over Georgia Tech, Burton dropped 21 points, eight assists and made three 3-pointers.

Freshman guard Braeden Shrewsberry gives the Fighting Irish a capable ball handler. Shrewsberry has a smooth jumper to keep the defense honest. He averaged 9.9 points, 2.5 rebounds and makes 36% of his 3-point attempts. In his last outing, Shrewsberry tallied 23 points and went 5-of-8 from downtown. See which team to pick here.

How to make Notre Dame vs. Wake Forest picks

SportsLine's model is leaning Over on the point total, projecting the teams to combine for 144 points. The model also says one side of the spread hits well over 50% of the time. You can only get the model's pick at SportsLine

So who wins Notre Dame vs. Wake Forest, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that has returned more than $1,700 on its college basketball picks this season, and find out.