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No. 20 North Carolina (8-2) will be looking to stay afloat in the ACC title race when it travels to Clemson (6-4) on Saturday afternoon. The Tar Heels need a pair of wins and some help from other teams in the conference to make the title game. They lost back-to-back games at the end of October, but they have responded with wins over Campbell and Duke. Clemson is accustomed to playing in the ACC championship, but it has already been eliminated heading into the final two games of the regular season. 

Kickoff is set for 3:30 p.m. ET on Saturday at Memorial Stadium. The Tigers are favored by 6.5 points in the latest Clemson vs. North Carolina odds, while the over/under is set at 58.5 points, per SportsLine consensus. Before entering any North Carolina vs. Clemson picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a strong profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

The model has set its sights on UNC vs. Clemson. You can head to SportsLine to see its picks. Here are several college football betting lines for the Clemson vs. UNC game:

  • Clemson vs. North Carolina spread: Clemson -6.5
  • Clemson vs. North Carolina over/under: 58.5 points
  • Clemson vs. North Carolina money line: Clemson -266, UNC +213
  • Clemson vs. North Carolina picks: See picks here
  • Clemson vs. North Carolina live stream: fubo (try for free)

Why Clemson can cover

Clemson is coming off two of its best performances of the season, beating then-No. 15 Notre Dame before crushing Georgia Tech. The Tigers covered the spread in both of those games, and they are in a good scheduling spot as they wrap up a three-game homestand. Running back Will Shipley, who missed some time due to an injury, rushed for 77 yards and a touchdown against Georgia Tech last week. 

Sophomore quarterback Cade Klubnik had one of his best outings of the season as well, completing 23 of 34 passes for 205 yards and four touchdowns. Clemson has won 23 of its last 26 November games, so the Tigers tend to put their best foot forward at this time of the year. North Carolina is coming off a double-overtime thriller, leaving Clemson as the more rested team in this matchup. 

Why North Carolina can cover

The Tar Heels should be the more motivated team on Saturday, as they are still alive for the ACC title. They avoided defeat in their double-overtime win against rival Duke last week, as running back Omarion Hampton racked up 169 rushing yards. Hampton is the ACC's leading rusher with 1,236 yards, while quarterback Drake Maye engineers an offense that leads the conference in points per game (39.9). 

Maye has thrown for 3,145 yards, 21 touchdowns and six interceptions, going over 300 yards in three of his last four games. Three Tar Heels have eclipsed 500 receiving yards, paced by junior wide receiver Devontez Walker (600). North Carolina has won seven of its last eight road games, and it has a significantly healthier roster right now. See which team to pick here.

How to make Clemson vs. North Carolina picks

The model has simulated North Carolina vs. Clemson 10,000 times and the results are in. The model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins Clemson vs. North Carolina, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the North Carolina vs. Clemson spread to jump on, all from the advanced computer model that's up well over $2,000 on its top-rated college football spread picks since its inception, and find out.