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The Navy Midshipmen aim for an upset against a familiar rival on Saturday afternoon. Ken Niumatalolo's team has lost three of the last four games, falling to 3-6 in 2022, but Navy has the chance to right the ship against the No. 20 Notre Dame Fighting Irish. Notre Dame is on a three-game winning streak with a 6-3 record this season. That includes a 21-point win over Clemson last week, and the Irish are 80-13-1 all-time against the Midshipmen.

Caesars Sportsbook lists Notre Dame as a 17-point favorite on the road, and kick-off is scheduled for 12 p.m. ET. The total number of points Vegas thinks will be scored, or the over/under, is 40 in the latest Notre Dame vs. Navy odds. Before you evaluate the Navy vs. Notre Dame match-up and make any college football predictions, you need to see the college football predictions and betting advice from SportsLine's advanced computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Notre Dame vs. Navy and locked in its picks and CFB predictions. You can head to SportsLine now to see the model's picks. Here are several college football odds and betting lines for Navy vs. Notre Dame:

  • Notre Dame vs. Navy spread: Notre Dame -17
  • Notre Dame vs. Navy over/under: 40 points
  • Notre Dame vs. Navy money line: ND -1000, Navy +650
  • ND: The Fighting Irish are 4-2 against the spread in the last six games
  • NAVY: The Midshipmen are 5-2 against the spread in the last seven games
  • Notre Dame vs. Navy picks: See picks at SportsLine

Why Notre Dame can cover

Notre Dame is stingy and well-coached defensively, and the Irish are reliable on that side of the ball. Notre Dame is also very strong on offense, however, and that includes 29.1 points per game for the season. On the ground, Notre Dame is averaging 195.1 rushing yards per game with 16 rushing touchdowns, and the Irish had a pair of 100-yard rushers in a 21-point win over Clemson last week. As a team, Notre Dame has exceeded 200 rushing yards in five of the last six games, and the Irish are converting 42.7% of third down chances this season.

Sophomore running backs Logan Diggs and Audric Estime each have 545 rushing yards or more this season, and quarterback Drew Pyne is 6-1 as a starter with 14 touchdown passes and only four interceptions. Tight end Michael Mayer is one of the best players in the country at the position with 624 yards and seven touchdowns this season, and Navy struggles in passing defense. The Midshipmen are allowing 8.8 yards per pass attempt and 275.0 passing yards per game, with opponents producing 20 touchdown passes and only six interceptions against Navy in 2022.

Why Navy can cover

Navy makes life difficult for opponents, both in preparation and execution. The Midshipmen deploy a triple-option offense that is unique in the college football world, and opponents are challenged to stay disciplined. Navy is in the top 10 of the country in rushing yards (2,132) this season, and the Midshipmen are elite in converting short-yardage situations. That includes a 54.8% fourth down efficiency rate, and Navy is also above-average in generating 8.3 yards per pass attempt. 

On defense, Navy is elite against the run, plugging gaps and allowing only 88.0 yards per game. That is No. 7 in the country, and the Midshipmen have allowed only five rushing touchdowns all season. Navy is yielding only 3.2 yards per carry and, for a Notre Dame team that leans heavily on the run, that is a potential advantage for the Midshipmen.

How to make Navy vs. Notre Dame picks

SportsLine's model is leaning Over on the total, projecting a combined 43 points. The model also says one side of the spread hits in over 60% of simulations. You can only see the model's CFB picks at SportsLine.

So who wins Notre Dame vs. Navy? And which side of the spread hits in over 60% of simulations? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.