The Indiana Hoosiers battle the second-ranked Ohio State Buckeyes on Saturday in a Big Ten Conference showdown. The Buckeyes (9-0, 6-0) have won 10 consecutive games dating back to last season, and have dominated Indiana, winning the last 26 meetings against it. Ohio State also holds a 76-12-5 edge in the all-time series that began in 1901. The Hoosiers (3-6, 1-5), meanwhile, will try to put an end to their six-game losing streak as well as snap their 26-game skid vs. Ohio State. Indiana last beat the Buckeyes in 1988, a 41-7 triumph.
Kickoff from Ohio Stadium in Columbus, Ohio, is set for noon ET. Ohio State averages 484.1 yards per game in 2022, best in the conference and 14th nationally, while Indiana averages 329, 12th in the Big Ten and 112th in the nation. The Buckeyes are favored by 40 points in the latest Indiana vs. Ohio State odds from Caesars Sportsbook, while the over-under for total points scored is 61. Before making any Ohio State vs. Indiana picks, you need to see the college football predictions and betting advice from SportsLine's advanced computer model.
The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.
Now, the model has set its sights on Ohio State vs. Indiana and locked in its picks and CFB predictions. You can head to SportsLine now to see the model's picks. Here are several college football odds and betting lines for Indiana vs. Ohio State:
- Ohio State vs. Indiana spread: Ohio State -40
- Ohio State vs. Indiana over/under: 61 points
- IU: The Hoosiers are 6-1 against the spread in their last seven games after allowing more than 40 points in their previous game
- OSU: The Buckeyes are 3-0-1 ATS in their last four home games
- Ohio State vs. Indiana picks: See picks at SportsLine
Why Ohio State can cover
Junior running back Miyan Williams leads the Buckeyes in rushing, carrying 102 times for 636 yards (6.2 average) and 12 touchdowns this season. He has rushed for 100 or more yards in three of the last five games, including 111 yards on 26 carries (4.3 average) and two touchdowns in last week's win at Northwestern. He also carried 21 times for 189 yards (9.0 average) and five TDs in a 49-10 win over Rutgers on Oct. 1. In a 52-21 victory over Wisconsin on Sept. 24, he carried just 11 times for 101 yards (9.2 average) and two scores.
The Buckeyes have not allowed Indiana a rushing touchdown or 100 yards rushing in a game in six years. Helping power the defense is senior linebacker Tommy Eichenberg, who leads the team with 85 tackles, including 53 solo. He also has 2.5 sacks for 12 yards, two pass breakups and one interception he returned 15 yards for a touchdown. Eichenberg is coming off back-to-back games in which he made double-digit tackles with 28 total at Northwestern and Penn State, including 10 solo in each game.
Why Indiana can cover
The Hoosiers may not have been able to beat the Buckeyes lately, but in three of the past 10 matchups, Indiana has been within one score of them. The Hoosiers have a one-two punch at running back in seniors Shaun Shivers and Josh Henderson. Shivers leads the team with 106 carries for 399 yards (3.8 average) and four touchdowns. He has a long run of 47 yards, and has 21 receptions for 125 yards and one score.
Henderson, meanwhile, has 63 rushes for 286 yards (4.5 average) and three TDs. He also has a long run of 23 yards. Henderson has been a force in the passing attack as well, catching 18 passes for 232 yards (12.9 average) and three touchdowns. His best game was an 11-carry, 65-yard and one touchdown effort against Western Kentucky in a 33-30 overtime win on Sept. 17. He also caught a pass for 32 yards in that game.
How to make Indiana vs. Ohio State picks
SportsLine's model is leaning Over on the total, projecting a combined 65 points. The model also says one side of the spread hits in almost 60% of simulations. You can only see the model's CFB picks at SportsLine.
So who wins Ohio State vs. Indiana? And which side of the spread hits in almost 60% of simulations? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.
