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The No. 19 Kansas Jayhawks will try to pick up their first win over the Oklahoma Sooners since 1997 when the teams square off on Saturday afternoon. Kansas remained inside the top 20 despite losing to TCU by a touchdown last week, marking just the third time the Jayhawks have been ranked heading into a matchup with the Sooners. Oklahoma is coming off a blowout loss to Texas and has dropped three straight games for the first time since 1998.

Kickoff is set for noon ET. The Sooners are 9-point favorites in the latest Oklahoma vs. Kansas odds from Caesars Sportsbook, while the over/under for total points scored is 64.5. Before entering any Kansas vs. Oklahoma picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Oklahoma vs. Kansas. You can head to SportsLine to see its picks. Here are several college football odds for Oklahoma vs. Kansas:

  • Oklahoma vs. Kansas spread: Oklahoma -9
  • Oklahoma vs. Kansas over/under: 64.5 points
  • Oklahoma vs. Kansas picks: See picks here

Why Oklahoma can cover

If there was ever a time for Oklahoma to be motivated, it would be this week. The Sooners are coming off the most lopsided shutout loss in school history, getting blanked by Texas in a 49-0 final. They were without starting quarterback Dillon Gabriel (head), but he could return for this game. 

Even if Gabriel is unable to play, senior running back Eric Gray should feast on Kansas' defense. Gray has gone over 100 rushing yards on three occasions this year, averaging 6.7 yards per carry overall this season. He is facing a Kansas defense that has allowed at least 27 points in four of its six games, and the Jayhawks are in an emotional letdown spot following their first loss of the campaign. Kansas is also likely to be without its starting quarterback on Saturday. 

Why Kansas can cover

This line opened with Oklahoma favored by a touchdown, but the early betting action has pushed the line to -9. The Sooners are reeling heading into this game though, with their latest game being a 49-0 loss to rival Texas. They lost to TCU by 31 points the week prior, giving them no momentum coming into this matchup against an inspired Kansas team.

The Jayhawks will not have star quarterback Jalon Daniels on the field for this game, but backup Jason Bean set a school record with four second-half touchdown passes last week. He is facing an Oklahoma defense that has allowed 48.3 points per game during its last three games. Kansas held a 10-0 lead at halftime last year, and the Jayhawks will be motivated to avenge their recent struggles against Oklahoma. 

How to make Kansas vs. Oklahoma picks

The model has simulated Oklahoma vs. Kansas 10,000 times and the results are in. The model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins Kansas vs. Oklahoma? And which side of the spread hits in well over 50% of simulations? Visit SportsLine now to see which side of the Oklahoma vs. Kansas spread you need to jump on Saturday, all from the model that has crushed its college football picks, and find out.