Sanders signed with the Panthers this offseason, and he's expected to be the lead running back in Carolina. Sanders is worth drafting as a No. 2 running back in all leagues as early as Round 4. Sanders is coming off a solid season in Philadelphia where he averaged 12.7 PPR points per game. He set career highs in carries (259), rushing yards (1,269) and rushing touchdowns (11), but he had career lows in targets (26), receptions (20) and receiving yards (78). With the Panthers, Sanders should be a three-down back, and the system and offensive line in Carolina should be favorable. However, the offense could struggle for the Panthers with rookie quarterback Bryce Young. If Sanders can see an uptick in the passing game -- he had at least 50 receptions in his rookie year in 2019 -- then he could emerge as a top-15 running back in all leagues, especially if he stays above 250 carries once again.