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Willis (undisclosed) was placed on the 49ers' injured reserve Wednesday.
Willis has spent the past two seasons with San Francisco, including 15 tackles and three sacks while playing 149 defensive snaps over 10 regular-season games in 2021. With the 27-year-old now set to sit out until at least Week 6, the 49ers also promoted Kemoko Turay from the practice squad to help shore up the team's defensive line.
