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National League Central rivals wrap up their three-game series on Wednesday afternoon when the Chicago Cubs (33-48) and the Milwaukee Brewers (47-36) square off. Milwaukee currently sits in first place in the division standings. Meanwhile, Chicago is in fourth place. Adrian Sampson (0-0, 3.38 ERA) gets the start for Chicago, while Corbin Burnes (7-4, 2.36 ERA) takes the mound for Milwaukee. 

First pitch is set for 2:10 p.m. ET. Milwaukee is the -267 money line favorite (risk $267 to win $100) in the latest Cubs vs. Brewers odds from Caesars Sportsbook, while Chicago is a +215 underdog. The over-under for total runs scored is seven. Before making any Brewers vs. Cubs picks, be sure to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it is 271-232 on top-rated MLB money-line picks since the start of the 2021 season, returning well over $500 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.

Now, the model has set its sights on Cubs vs. Brewers, and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Brewers vs. Cubs:

  • Cubs vs. Brewers moneyline: Milwaukee -267, Tampa Bay +215
  • Cubs vs. Brewers run-line: Chicago +1.5 (+105)
  • Cubs vs. Brewers over-under: 7 runs
  • CHC: The Cubs are 5-2 in their last seven overall
  • MIL: The Brewers are 4-0 in their last four games following a loss
  • Cubs vs. Brewers picks: See picks here
Featured Game | Milwaukee Brewers vs. Chicago Cubs

Why you should back the Brewers

Designated hitter Andrew McCutchen brings athleticism, leadership, and plate awareness onto the diamond. McCutchen is instinctive with his compact swing. The five-time All-Star has a batting average of .249 with seven home runs and 32 RBIs. On July 1, he was 3-for-6 with a triple and two runs scored.

Shortstop Willy Adames generates plenty of bat speed with superb strength. Adames can drive the ball into the gaps and produce extra-base hits. The 26-year-old is a smooth defender who owns a strong throwing arm. He's second on the team in both home runs (16) and RBIs (45). On July 30, he went 1-for-5 with a double and one run scored. 

Why you should back the Cubs

Third baseman Patrick Wisdom is a good athlete who's a reliable defender in the corner. Wisdom is able to make quick reads and deliver the ball with accuracy. The 30-year-old has displayed home-run and run-producing abilities. He currently leads the team in homers (17) and RBIs (45). On July 5, he was 2-for-4 with a double. 

Left fielder Ian Happ is a refined hitter with exceptional hands. Happ is a switch-hitter with terrific instincts at the plate and on the defensive end. The 27-year-old has a batting average of .283 with eight home runs and 38 RBIs. On July 1, he was 3-for-5 with two triples. 

How to make Brewers vs. Cubs picks

SportsLine's model is leaning over on the total, projecting 8.7 runs. The model also says one side of the money line has all the value. You can only get the model's MLB picks at SportsLine.

So who wins Cubs vs. Brewers? And which side has all the value? Visit SportsLine now to see which side of Brewers vs. Cubs you need to jump on Wednesday, all from the model that has crushed its MLB picks, and find out.