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The Boston Red Sox (3-3) host the Minnesota Twins (2-4) on Friday afternoon for the first matchup of a four-game series. The Twins are looking to halt a two-game skid after being outscored 14-2 in their last two contests. Meanwhile, Boston has won two straight games, scoring 14 runs during that stretch. Nick Pivetta (0-1, 6.35 ERA) gets the start for Boston, while Joe Ryan (0-1, 4.50 ERA) is on the hill for Minnesota.

First pitch is set for 2:10 p.m. ET. Boston is the -130 money-line favorite (risk $130 to win $100) in the latest Twins vs. Red Sox odds from Caesars Sportsbook, while Minnesota is a +110 underdog. The over-under for total runs scored is 10. Before making any Twins vs. Red Sox picks, you need to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

This model, which simulates every game 10,000 times, enters Week 2 of the 2022 season on a 216-181 roll on top-rated MLB money-line picks that dates back to last season, returning over $900 for $100 players. Anyone following it has seen huge returns.

Now, the model has locked in on Red Sox vs. Twins, and just locked in its picks and MLB predictions. You can visit SportsLine now to see the model's picks. Here are the MLB odds and trends for Twins vs. Red Sox:

  • Red Sox vs. Twins money line: Boston -130, Minnesota +110
  • Red Sox vs. Twins run line: Boston -1.5 (+145)
  • Red Sox vs. Twins over-under: 10 runs
  • BOS: The Red Sox are 6-1 in their last seven games with the total set at 6.5 or lower
  • MIN: The Twins are 4-1 in their last five during Game 1 of a series
Featured Game | Boston Red Sox vs. Minnesota Twins

Why you should back the Red Sox

Left fielder Alex Verdugo is a good athlete and can cover a lot of ground in the outfield. Verdugo has a great batters eye and will draw walks. He has a batting average of .300 with one home run and four RBIs. In his last matchup against the Detroit Tigers, Verdugo had a double, one run batted, and drew two walks. 

Shortstop Xander Bogaerts is a naturally gifted hitter with a terrific swing. He was the power to hit the ball to all parts of the field with regularity. Bogaerts also has a good arm to make any throw on the diamond. The three-time All-Star is fourth on the team in batting average (.263) with five total hits. On April 8th, Bogaerts finished with three hits and scored two runs. 

Why you should back the Twins

Catcher Gary Sanchez has excellent power. Behind the plate, he has a great throwing arm. Sanchez has tallied a hit in three of the five games he's played in. On April 10, the two-time All-Star went 2-for-4 with a grand slam and an additional RBI. Sanchez also recorded a double and scored a run.

Shortstop Jorge Polanco is an excellent defender in the infield for Minnesota. He's a switch-hitter with great bat control and a solid line-drive swing. Polanco is 5-for-14 in his last 19 bat attempts, including a home run, three RBIs and a double. Second baseman Luis Arraez has good bat speed and consistently makes contact with the baseball. Arraez has a batting average of .313 with an on-base percentage of .813. 

How to make Twins vs. Red Sox picks

SportsLine's model is leaning over on the run total, as the simulation suggests the teams will combine for 10.3 runs. It also says one side of the money line has all the value. You can only get the model's pick at SportsLine

So who wins Red Sox vs. Twins? And which side of the money line has all the value? Visit SportsLine now to see which side to jump on, all from the advanced model that has crushed its top-rated MLB picks, and find out.