The Boston Celtics will take on the Cleveland Cavaliers at 7 p.m. ET on Monday at Rocket Mortgage FieldHouse. Cleveland is 9-5 overall and 4-2 at home, while the Celtics are 6-7 overall and 4-4 on the road. Boston has dominated this series in recent years, winning nine of the last 12 games against the Cavaliers. However, the Cavaliers have won each of the last three meetings between these two teams.

Boston is favored by 2.5-points in the latest Cavaliers vs. Celtics odds from Caesars Sportsbook, and the over-under is set at 199.5. Before entering any Celtics vs. Cavaliers picks, you'll want to see the NBA predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $9,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model enters Week 5 of the 2021-22 NBA season up over $900 on all top-rated NBA picks this season. It's also on a stunning 113-75 roll on top-rated NBA picks against the spread that dates back to last season. Anyone following it has seen huge returns.

Now, the model has set its sights on Cavaliers vs. Celtics. You can head to SportsLine to see its picks. Here are several NBA betting lines for Cavaliers vs. Celtics:

  • Cavaliers vs. Celtics spread: Boston -2.5
  • Cavaliers vs. Celtics over-under: 199.5 points
Featured Game | Cleveland Cavaliers vs. Boston Celtics

What you need to know about the Celtics 

These two teams squared off on Saturday. It was close but no cigar for Boston as the Celtics fell 91-89 to Cleveland. Boston was up 52-38 at the end of the half but couldn't hold on to the lead. Center Robert Williams III put forth a good effort for the losing side as he posted a double-double with 16 rebounds and 12 points in addition to three blocks.

Despite suffering a setback on Saturday, the Celtics will be confident they can secure the victory on Monday. That's because Boston has won nine of its last 12 meetings with Cleveland. However, the Celtics are 2-7-1 against the spread in their last 10 road games against the Cavaliers. 

What you need to know about the Cavaliers 

The Cavaliers have been one of the biggest surprises in the NBA this season. Cleveland enters Monday's matchup having won six of its last seven games. The Cavaliers have been able to secure those positive results thanks in large part to their suffocating defense. In fact, Cleveland ranks second in the NBA in scoring defense, giving up just 101.3 points per game.

Offensively, the Cavaliers are led by point guard Darius Garland. The 21-year-old is averaging 16.8 points, 7.1 assists and 2.3 rebounds per game. Rookie Evan Mobley is also one of Cleveland's top playmakers, averaging 15.6 points, 7.9 rebounds, 2.3 assists and 1.1 steals per game. 

How to make Cavaliers vs. Celtics picks

The model has simulated Cavaliers vs. Celtics 10,000 times and the results are in. We can tell you that the model is leaning over, and it's also generated a point-spread pick that is hitting in 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Celtics vs. Cavaliers? And which side of the spread hits 60 percent of the time? Visit SportsLine here to see which side of the spread you should back, all from the model that's crushed its NBA picks