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The Detroit Pistons will take on the Boston Celtics at 7:30 p.m. ET on Wednesday at TD Garden. Boston is 34-25 overall and 20-10 at home, while the Pistons are 12-45 overall and 4-25 on the road. The Celtics will try to extend their winning streak to 10 games before pausing for the NBA All-Star break. 

Boston is favored by 12.5-points in the latest Celtics vs. Pistons odds from Caesars Sportsbook, while the over-under is set at 213.5. Before entering any Pistons vs. Celtics picks, you'll want to see the NBA predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons. The model enters Week 17 of the 2021-22 NBA season on a stunning 67-39 roll on all top-rated NBA picks, returning over $2,200. Anyone following it has seen huge returns.

Now, the model has set its sights on Celtics vs. Pistons. You can head to SportsLine to see its picks. Here are several NBA betting lines for Celtics vs. Pistons:

  • Celtics vs. Pistons spread: Celtics -12.5
  • Celtics vs. Pistons over-under: 213.5 points

What you need to know about the Celtics

Boston is the hottest team in the NBA, with its last loss coming on Jan. 28 in Atlanta. The Celtics have the longest active winning streak in the league, extending their streak to nine games with a 135-87 blowout over Philadelphia on Tuesday. Jaylen Brown led the way with 29 points on 10-of-17 shooting, knocking down five of his seven 3-point attempts. 

The Celtics also set a single-game franchise record with 25 made 3-pointers in the win. Small forward Jayson Tatum has been the team's leading scorer overall this season, averaging 25.8 points and 8.5 rebounds per game. Boston has covered the spread in four of its last five games. 

What you need to know about the Pistons

Detroit has been trending in the opposite direction, losing eight consecutive games coming into this contest. The latest setback came in a 103-94 loss at Washington on Monday, giving the Pistons a 4-25 record on the road this season. Saddiq Bey scored a team-high 24 points, marking the fifth time in seven games that he has scored at least 20 points. 

Marvin Bagley III, who was acquired from Sacramento in a trade last week, scored 10 points and grabbed eight rebounds in his Detroit debut. Rookie Cade Cunningham is averaging 15.6 points, 5.4 rebounds and 5.1 assists per game. The Pistons have covered the spread in five consecutive games against Boston. 

How to make Pistons vs. Celtics picks

The model has simulated Celtics vs. Pistons 10,000 times and the results are in. We can tell you that the model is leaning under, and it's also generated a point-spread pick that is hitting in almost 70 percent of simulations. You can only see the pick at SportsLine.

So who wins Pistons vs. Celtics? And which side of the spread covers almost 70 percent of the time? Visit SportsLine now to find out, all from the model that has crushed its NBA picks.