The Jacksonville Jaguars will try to improve to 2-0 against the Buffalo Bills in London when the teams square off in an AFC showdown on Sunday at Tottenham Hotspur Stadium. Jacksonville (2-2) posted a victory against Buffalo in England's capital in 2015, when it edged the Bills 34-31 at Wembley Stadium. The Jaguars improved to 5-5 in London last week after cruising past Atlanta 23-7 at Wembley. Buffalo (3-1) rolled over Miami 48-20 in Week 4 for its third straight win by 28 or more points.
Kickoff is set for 9:30 a.m. ET. Buffalo is a 5.5-point favorite in the latest Bills vs. Jaguars odds, while the over/under for total points scored is 48.5. Before making any Jaguars vs. Bills picks of your own, you need to see the NFL predictions and betting advice from SportsLine's Advanced Computer Model.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 5 of the 2023 NFL season on an incredible 168-118 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 22-10 roll on top-rated NFL picks since Week 7 of last season.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.
Now, the model has set its sights on Bills vs. Jaguars and just locked in its picks and NFL predictions. You can head to SportsLine now to see the model's picks. Now, here are several NFL odds and betting lines for Jaguars vs. Bills:
- Bills vs. Jaguars spread: Buffalo -5.5
- Bills vs. Jaguars over/under: 48.5 points
- Bills vs. Jaguars money line: Buffalo -247, Jacksonville +201
- BUF: Bills are 5-1 against the spread in their last six games
- JAX: Jaguars are 5-0 ATS in their last five contests away from Jacksonville
- Bills vs. Jaguars picks: See picks at SportsLine
Why the Bills can cover
Buffalo hasn't trailed since late in the first quarter of its Week 2 victory against Las Vegas and has outscored the opposition 123-26 since allowing the first touchdown of that contest. The Bills have recorded 14 offensive touchdowns in that span, with Josh Allen having a hand in 10 of them. The 27-year-old quarterback has thrown for eight TDs and run for two others, with half of his scoring passes coming last Sunday against the Dolphins.
That contest was the 27th in which Allen threw and ran for a touchdown, ranking him fourth on the all-time list. He capped the scoring versus Miami with his 40th career rushing TD, which tied him with Jack Kemp for third among quarterbacks in NFL history, three behind Steve Young for second place. Allen connected with Stefon Diggs for three scores and Gabe Davis for the third consecutive game, marking the 10th time in his career he's had four touchdown tosses in a contest. See which team to pick here.
Why the Jaguars can cover
Jacksonville's only previous appearance at Tottenham Hotspur Stadium was a memorable one, as it posted a 23-20 victory over Miami in Week 6 of the 2021 season to halt its 20-game losing streak. It also was the first NFL win for quarterback Trevor Lawrence, who completed 25-of-41 pass attempts for 319 yards and a touchdown. The Jaguars recorded their second win of that campaign two weeks later, when they were 15.5-point underdogs but limited Buffalo to a pair of field goals in a 9-6 triumph.
Wideout Calvin Ridley has hauled in fewer than four passes the last three weeks after having eight in his team debut in Week 1, but one of his two catches last weekend was for a touchdown. Jacksonville's leading receiver against the Falcons was Christian Kirk, who had eight receptions for 84 yards. Running back Travis Etienne Jr. has enjoyed playing in London in his brief NFL career, rushing 44 times for 211 yards and a TD in two contests. See which team to pick here.
How to make Bills vs. Jaguars picks
SportsLine's model is leaning Under the point total, calling for 48 combined points. The model also says one side of the spread hits in over 60% of simulations. You can only see the model's pick at SportsLine.
So who wins Bills vs. Jaguars in London, and which side of the spread hits in over 60% of simulations? Visit SportsLine now to see which side of the Jaguars vs. Bills spread you need to jump on Sunday, all from the model on a 168-118 roll on its top-rated NFL picks, and find out.
