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A rivalry dating back to the AFL will be renewed on Monday Night Football when the Buffalo Bills battle the New York Jets in the final game of the Week 1 NFL schedule. The Bills, who have won five of the past six meetings, are coming off their third consecutive AFC East championship with a 13-3 record. The Jets, who last won an AFC East title in 2002, are looking to improve on a 7-10 mark under third-year coach Robert Saleh. Monday Night Football will also mark the New York debut of former Packers standout quarterback Aaron Rodgers, who spent his first 18 seasons in Green Bay. 

Kickoff from MetLife Stadium in East Rutherford, N.J., is set for 8:15 p.m. ET. The Bills are two-point favorites in the latest Bills vs. Jets odds, while the over/under for total points scored is 44.5. Before making any Jets vs. Bills picks, be sure to check out the NFL predictions and betting advice from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the 2023 NFL season on an incredible 163-113 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 17-6 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now the model has its sights set on Jets vs. Bills and just locked in his MNF picks and predictions. You can visit SportsLine now to see the model's picks. Here are the NFL odds and betting lines for Bills vs. Jets:

  • Bills vs. Jets spread: Bills -2
  • Bills vs. Jets over/under: 44.5 points 
  • Bills vs. Jets money line: Buffalo -129, New York Jets +110
  • BUF: Bills have hit the first quarter over in 15 of their last 21 games 
  • NYJ: Jets have scored last in 12 of their last 17 games 
  • Bills vs. Jets picks: See picks at SportsLine

Why the Bills can cover

Quarterback Josh Allen has played well under the spotlight of Monday Night Football. In his past five starts on MNF, he has passed for 1,510 yards (302 per game) with 16 touchdowns with one interception and a 119.7 rating. He had three rushing touchdowns in two games against the Jets last season. Allen had a solid season a year ago, completing 359 of 567 passes (63.3%) for 4,283 yards and 35 touchdowns. He was intercepted 14 times, but had a rating of 96.6.

On defense, defensive end Greg Rousseau has made life miserable for opposing quarterbacks. He tied for the team lead with a career-high eight sacks in 13 games in 2022. In a 20-12 win over the New York Jets on Dec. 11, he had two sacks and a forced fumble. He finished the year with 37 tackles, including 27 solo, with four pass breakups. See which team to pick here.

Why the Jets can cover 

Rodgers, who has 59,055 career passing yards, had a solid season last year despite being banged up for much of it. He finished 2022 by completing 350 of 542 passes (64.6%) for 3,695 yards and 26 touchdowns, including a long TD pass of 58 yards. He was intercepted just 12 times, but sacked 32 times, and had a rating of 91.0. In 18 career starts on Monday Night Football, Rodgers has posted a 104.9 rating with 41 touchdowns, including 38 passing, with 11 interceptions.

Helping lead the Jets' defense is cornerback Sauce Gardner. He was named the Associated Press Defensive Rookie of the Year last season after leading the league with 20 pass breakups, the most by a rookie since 2015. He had two pass breakups and an interception in two games against Buffalo. Gardner was fifth on the team in tackles with 75, including 51 solo. See which team to pick here.

How to make Bills vs. Jets picks

SportsLine's model is leaning under the point total. In fact, it's calling for 43 combined points It has also generated an against-the-spread pick that hits in over 50% of simulations. You can only get the model's pick at SportsLine

So who wins Jets vs. Bills on Monday Night Football, and which side of the spread cashes in over 50% of simulations? Visit SportsLine now to see which side of the Jets vs. Bills spread to jump on, all from the advanced model that finished up more than $7,000 on its NFL picks since its inception, and find out.