NFL Week 3 betting and fantasy live updates: Latest odds and info on line moves, injuries and more

It's Week 3 in the NFL, and with it comes a potential conference championship matchup on both sides of the league. In the NFC, a white-hot Seahawks team welcomes the Cowboys into town after Dak Prescott potentially saved Dallas' season with a late-game rally against the Falcons in Week 2. In the AFC team, two Super Bowl favorites square off on Monday night with the Chiefs heading to Baltimore to face the Ravens.

But those aren't the only big games on the board. The Rams and Bills battle in a matchup of 2-0 teams, the Raiders look to stay hot when they head to Foxborough to battle a Patriots team coming off a close loss, the Texans look to break through their brutal early-season schedule with a trip to Pittsburgh, and the Saints will try to bounce back from a surprising Monday night loss when the undefeated Packers come to town for Sunday Night Football in another potential NFC Championship matchup.

We're here to track all the betting and fantasy angles you need to know in the run up to kickoff of the Sunday slate, including line movements, injury updates, inactive lists, depth chart news, the buzz on the betting market, key information from our partners at William Hill Sportsbook and plenty more.

Here's a look at the odds for each Week 3 game as of 1 p.m. ET Sunday:

Rams at Bills (-1.5), O/U 46.5
Washington at Browns (-7), O/U 45
Bengals at Eagles (-5.5), O/U 46.5
Texans at Steelers (-4), O/U 46.5
49ers (-3) at Giants, O/U 43.5
Titans (-2.5) at Vikings, O/U 49
Raiders at Patriots (-7), O/U 47
Bears at Falcons (-2.5), O/U 46
Jets at Colts (-11.5), O/U 43.5
Panthers at Chargers (-6.5), O/U 43.5
Buccaneers (-6) at Broncos, O/U 42.5
Lions at Cardinals (-5.5), O/U 55.5
Cowboys at Seahawks (-5.5), O/U 56.5
Packers at Saints (-3), O/U 52
Chiefs at Ravens (-3.5), O/U 54.5

Before you get to the latest buzz, let's make sure you have all the right tools to dominate Week 3:

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That's going to do it for our pregame coverage of the fantasy and betting angles to know for Week 3. Thanks for joining us, and good luck with your tickets and lineups!

September 27, 2020, 5:01 PM
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Steelers gain ground ahead of kickoff

After watching the market move against them earlier on Sunday, the Steelers find themselves reinstalled as four-point favorites with just a few minutes until kickoff. Interestingly, the first-half spread for the game is Steelers -3 flat, so if this matchup is between 3.5 and 4 for the full game, the Texans would appear to be a nice value on that first-half line.

September 27, 2020, 4:53 PM
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Market holding steady

After a flurry of action all morning on the Week 3 slate, the lines remain unmoved over the last 30 minutes with about as long left until the first kickoff of the day. You can check out our rundown of the slate here, with expert picks from every game along with SportsLine advice, the Pick Six Podcast, survivor pool options and more.

September 27, 2020, 4:39 PM
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Saints juiced up, move off 3 coming?

The Saints have been locked in as just three-point favorites for their game against the 2-0 Packers on Sunday night all week despite having been 5.5-point favorites on the lookahead line. But the line might not stay a 3 for much longer, with the Saints juiced to -125 on the spread. Bettors may have to act quickly to get Packers +3.5 if the line moves, as the books aren't likely to leave it at 3.5 if they start taking in a large amount of action on the underdogs.

September 27, 2020, 4:08 PM
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49ers line makes anticipated move

Earlier on Sunday, we saw the juice shift heavily in the Giants' favor at +3.5 in their matchup with the 49ers, and by noon ET the line made the jump we expected, with the 49ers just three-point favorites in the game. The total has also steadily risen in this game, from 41.5 in the middle of the week to 43.5 with about an hour left until kick. Clearly the market is expecting the 49ers' defensive injuries to matter more than the absences on the offensive side of the ball for both teams.

September 27, 2020, 4:05 PM
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Cowboys-Seahawks line continues to shuffle

After watching the line in Cowboys-Seahawks sink from Seahawks -5, where it had been all week, to Seahawks -4.5 early on Sunday, it's now flipped in the other direction, with the Seahawks as 5.5-point favorites as of noon ET. With 5 not being a key number, it's unlikely pros are betting both sides of this matchup and trying to middle the game, so take this as the market not being certain what to expect in this game.

September 27, 2020, 4:01 PM
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Total falls with Julio sidelined

The total for Bears-Falcons has already dipped a full point with news that Julio Jones is inactive for the game, as the number now sits at 46 at William Hill Sportsbook. The Falcons have seen Russell Gage emerge as a reliable weapon over the first two weeks, and Calvin Ridley has the look of a No. 1 receiver, but we'll see if both players can keep up their early-season performance without Julio to draw attention.

September 27, 2020, 3:57 PM
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Line moves back to Bills

After seeing their line fall all the way down to one point, the Bills gained some ground back in their matchup with the Rams, which now sits at Bills -1.5. Both teams will be missing their rookie running backs in the game, but neither absence should have much effect on the line.

September 27, 2020, 3:55 PM
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Injuries affecting Raiders line?

Though both Josh Jacobs and Darren Waller are active for their game against the Patriots, reports that the pair could be limited throughout the game may be affecting the line, which has jumped a half-point to Patriots -7. Anyone who managed to hop on Bill Belichick's squad earlier in the week appears to be in line to get closing line value in this matchup.

September 27, 2020, 3:54 PM
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Bears inactives: Khalil Mack active

Inactives: CB Duke Shelley, OLB Trevis Gipson, OL Arlington Hambright, DT Daniel McCullwrs, WR Riley Ridley

Khalil Mack playing today is the biggest name out of this bunch. The star linebacker was officially ruled as questionable for Week 3 by Chicago, but he's ready to go. Riley Ridley -- the brother of Falcons star receiver Calvin Ridley -- is inactive. 

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Washington inactives: No surprises

Inactives: QB Alex Smith, RB Bryce Love, CB Danny Johnson, LB Cole Holcomb, T David Sharpe, T Saahdiq Charles, DE James Smith-Williams

For the third consecutive game, both Alex Smith and Bryce Love are inactive. Although both Smith and Love received a lot of training camp buzz, thus far, neither factors into the team's 2020 plans. Washington is relatively healthy -- specifically on the offensive side of the ball. Morgan Moses missed practice earlier this week but will play in this one.

September 27, 2020, 3:49 PM
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Texans inactives: Duke still out

Inactives: RB Duke Johnson, CB Cornell Armstrong, OLB Jonathan Greenard, LB Peter Kalambayi, OT Charlie Heck, DT Ross Blacklock

The Texans remain without pass-catching weapon Duke Johnson at running back, leaving David Johnson to handle as much of the load as he can at the position. Kenny Stills was ruled questionable for this game due to an illness, but he's good to go after avoiding the inactive list.

September 27, 2020, 3:47 PM
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49ers inactives: No surprises 

Inactives: QB Jimmy Garoppolo, RB Raheem Mostert, TE George Kittle, DE Dee Ford, LB Dre Greenlaw, CB Ahkello Witherspoon, OL Tom Compton

San Francisco ruled most of these players out at the end of the week. The only real question was whether or not Witherspoon would play after officially being listed as questionable. He won't, which only adds to the 49ers theme of missing key starters on the defensive side of the ball. 

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Rams inactives: Akers is OUT

Inactives: RB Cam Akers, WR Trishton Jackson, TE Brycen Hopkins, C Brian Allen, DL Eric Banks

Akers injured his rib last week after drawing his second straight starts and did not return. With Akers out, last year's disappointing rookie Darrell Henderson finally got rolling in a back way for the Rams. We expect them to ride the hot hand -- but even if that is Henderson again -- Malcolm Brown will get his work as well. Of note, RB Raymond Calais is active for the first time this season.

September 27, 2020, 3:46 PM
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Steelers inactives: DeCastro back

Inactives: QB Josh Dobbs, LB Ulysees Gilbert III, DT Carlos Davis, T Derwin Gray, TE Zach Gentry

The Steelers had no one on their final injury report for the week, so they'll enjoy their best health of the season in the Week 3 game against the Texans. David DeCastro is back at guard to help fortify the offensive line.

September 27, 2020, 3:45 PM
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Bengals inactives: Daniels cleared

Inactives: WR John Ross, RB Trayveon Williams, DT Geno Atkins, DT Andrew Brown, LB Markus Bailey, K Austin Seibert

The Bengals will have their two questionable players available for their matchup with the Eagles, as defensive tackle Mike Daniels and safety Shawn Williams avoid the inactive list. However, the middle of the defensive line could be an issue with Atkins sidelined despite Daniels being able to play.

September 27, 2020, 3:43 PM
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Giants inactives: Freeman will play

Inactive: CB Brandon Williams, DB Adrian Colbert, LB TJ Brunson, OT Jackson Barton, TE Eric Tomlinson, DL RJ McIntosh

Devonta Freeman was signed on Tuesday, practiced on Wednesday and will now be active for his first game as a New York football Giant. While his role remains unknown, it's hard to imagine him playing a major role after just picking up the playoff a few days ago. After being inactive last week, Wayne Gallman is active today. I would expect Gallman to draw the start with Dion Lewis playing on all pass downs and likely seeing the majority of snaps in this backfield.

September 27, 2020, 3:42 PM
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Raiders inactives: Jacobs, Waller active

Inactives: T Trent Brown, DE Kendall Vickers, LB Nick Kwiatkoski,  WR Henry Ruggs, CB Madre Harper, CB Amik Robertson, T Sam Young

After being ruled as questionable for their Week 3 matchup with New England, running back Josh Jacobs and tight end Darren Waller will play today against the Patriots. CBS Sports' Tracy Wolfson reports, however, that both are not 100% and, while they will start, they could be limited throughout the game. May need to temper expectations from both of these fantasy studs. 

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Browns inactives: Ward active

Inactives: WR Donovan Peoples-Jones, CB Greedy Williams, LB Jacob Phillips, DE Olivier Vernon, G Evan Brown, WR Rashard Higgins

All three questionable players are active for this matchup, with Denzel Ward starting at corner and Adrian Clayborn all clear to start in place of the injured Vernon. But one questionable player, Mack Wilson, has been replaced in the starting lineup by Malcolm Smith at linebacker, the team announced.

September 27, 2020, 3:40 PM
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Vikings inactives: Injuries piling up at CB

Inactive: CB Mike Hughes, CB Cameron Dantzler, WR K.J. Osborn, WR Tajae Sharpe, DE Eddie Yarbrough, DT James Lynch, OT Oli Udoh

The key story here are the injuries at CB for the Vikings with both Hughes and Dantzler out this week. Minnesota's secondary has surprisingly been among the NFL's worst through two weeks and they take a massive hit this week without Hughes and Dantzler. You should upgrade Corey Davis and Jonnu Smith in this matchup. Adam Humphries becomes an intriguing flyer play at FLEX with AJ Brown (knee) still out.

September 27, 2020, 3:38 PM
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Patriots inactives: No surprises

Inactives: RB James White, LB Anfernee Jennings, TE Dalton Keene, T Korey Cunningham, QB Jarrett Stidham, CB Myles Bryant

No true surprises here. N'Keal Harry was late coming out onto the field during warmups which did raise some eyebrows, but the second-year receiver is active and looking to build off a strong performance in Week 2. For the third straight week, Brian Hoyer is Cam Newton's backup, leaving Jarrett Stidham as a healthy scratch. 

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Eagles inactives: Cox active

Inactives: QB Nate Sudfeld, RB Jason Huntley, WR Alshon Jeffery, WR Jalen Reagor, G Jamon Brown, DL Casey Toohill, S Rudy Ford

Fletcher Cox is good to go after drawing a questionable tag on the team's final injury report. Without Jeffery or Reagor, the passing game will have to rely on DeSean Jackson and the team's dynamic duo at tight end.

September 27, 2020, 3:36 PM
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Bills inactives: Moss out, Singletary's role expands

Inactive: RB Zack Moss, QB Jake Fromm, TE Dawson Knox, OL Ike Boettger, DE Darryl Johnson LB Del'Shawn Phillips

The key inactive here is Moss. In the first two weeks, Moss has seen the majority of red zone work and has taken a near 50-50 split in the backfield with Devin Singeltary. In Week 3, Singletary will get the bulk of touches and likely be used in the red zone. While Buffalo will spell him with TJ Yeldon, don't expect Yeldon to play the same role Moss did.

September 27, 2020, 3:35 PM
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Falcons inactives: Julio Jones out

Falcons inactives: Julio Jones, Kendall Sheffield, Ricardo Allen, Foye Oluokun, Kaleb McGary, Takk McKinley, and Deadrin Senat

Julio Jones (hamstring) is the big name here. Atlanta held out hope that he'd be able to go, but ultimately just wasn't ready. This bumps up the targets for receivers Calvin Ridley and Russell Gage along with tight end Hayden Hurst.  

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Titans inactives: No surprises

Inactives: WR A.J. Brown, OL Aaron Brewer,  DL Matt Dickerson,  DB Chris Jackson,  OLB Derick Roberson,  TE Geoff Swaim

The Titans ruled three players out on their final injury report but had no other designations, so there are no surprises on their list. With Brown sidelined again, Corey Davis and Adam Humphries will look to take advantage of an excellent matchup against the Minnesota secondary.

September 27, 2020, 3:34 PM
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49ers-Giants about to fall?

The 49ers were four-point favorites for much of the week but found themselves favored by 3.5 entering Sunday. The line appears to be close to moving another half-point, with the Giants juiced to -120 at +3.5. With so many injuries for San Francisco on both sides of the ball, it wouldn't be a surprise at all to see the Giants pull off the upset at home (they sit as +155 underdogs on the moneyline).

September 27, 2020, 3:16 PM
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Market fading the Steelers

The 2-0 Steelers opened as six-point favorites for their matchup against the 0-2 Texans, but that line quickly dropped to Steelers -4 and stayed their for a majority of the week. It's moved off that spot Sunday morning, however, with the Texans catching interest and shifting the line to Steelers -3.5. It's worth noting as well that the juice is on the Texans' side right now at -115, so it's closer to dropping again to 3 rather than moving back to 4.

September 27, 2020, 3:14 PM
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Cowboys-Seahawks move short-lived

While the line for the biggest matchup of the Sunday late afternoon slate was nailed on at Seahawks -5 all week, an early Sunday move down to Seahawks -4.5 made it seem we could see a steam toward the Cowboys. But that move was short-lived, with the Seahawks back as five-point favorites later in the morning.

September 27, 2020, 3:06 PM
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Bears catching less than a field goal

We talked about the juice in the Bears-Falcons game earlier this morning, and the line eventually made the move off three in line with the earlier shift, as it now sits at Falcons -2.5. This game figures to settle at 3 before kickoff, so expect many of the pros holding a Bears +3.5 ticket from earlier in the week to jump on the Falcons at -2.5 hoping to middle the game.

September 27, 2020, 3:00 PM
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Eagles catch steam on Sunday

After moving from -4 to -4.5 early on Sunday morning, the Eagles are on the move again, with the matchup spiking to Eagles -5.5 before the 11 a.m. ET hour. This matchup opened at Eagles -6.5 last Sunday, so if the market believes the books had the line right initially, we could see more action on the Eagles' side of the line.

September 27, 2020, 2:57 PM
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