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With six games taking place between Saturday and Monday, the 2024 NFL Super Wild Card Weekend should live up to its name. The expanded NFL playoffs means even more opportunity to build winning NFL bets without being boxed in by unappealing lines. The Steelers won and covered in their last three games to sneak into the NFL playoff bracket, but now their momentum will be bested by the red-hot Bills, who won six of seven to come from out of nowhere and steal the AFC East.

The latest NFL Super Wild Card Weekend odds list Buffalo as a 10-point favorite with Pittsburgh missing NFL Defensive Player of the Year candidate T.J. Watt (knee). So which side should you be backing in that contest and what other NFL lines should you be targeting as you build your NFL parlay picks? Before you make any Super Wild Card Weekend NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the 2024 NFL playoffs on an incredible 183-129 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 37-21 roll on top-rated picks since Week 7 of last season and has nailed seven straight top-rated picks entering the 2024 NFL playoffs.  

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in six confident NFL best bets for Super Wild Card Weekend. If you successfully parlay its picks, you'd be looking at a massive payout of almost 50-1. You can only see the model's Super Wild Card Weekend NFL picks at SportsLine.

Top Super Wild Card Weekend NFL picks

After simulating every game 10,000 times, the model is high on the Detroit Lions (-3) to cover at home against the Los Angeles Rams on Sunday at 8 p.m. ET. It's been a historic season for Detroit, as the Lions ended a 30-year drought with regards to divisional titles by comfortably winning the NFC North. Now, they'll look to end a 32-year winless drought in the NFL playoffs with their seventh home postseason game in the 93-year existence of the franchise.

The Lions were top five in the NFL in passing offense (second) and rushing offense (fifth). That balance should pose problems for a Rams that was pretty middle-of-the-road in all aspects this season (19th in scoring defense and 20th in total defense). They have a weapon-filled offense with Jared Goff, David Montgomery, Jahmyr Gibbs and Amon-Ra St. Brown even if Sam LaPorta (knee) sits. The model is predicting that the Lions cover in well over 50% of simulations. See which other NFL parlay picks to make here.

How to make Super Wild Card Weekend NFL parlays

The model also jumped on five other NFL matchups where it says the line is way off, including a pair of underdogs that have a chance to win outright. You can only see the model's Super Wild Card Weekend NFL best bets and parlay at SportsLine

What are the model's top Super Wild Card Weekend NFL picks, and which other NFL matchups should you target for a hefty payout of almost 50-1? Visit SportsLine now to see the Super Wild Card Weekend NFL best bets from a model on a 183-129 run on top-rated picks, and find out.