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After winning the second-ever European Championship crown in 1964, Spain appeared in only six of the following 10 tournaments and failed to win another title. The Spanish side ended the drought in 2008 and made it back-to-back championships four years later before being ousted by the Italians in the round of 16 in 2016. Spain will have revenge on its mind Tuesday as it faces Italy in the Euro 2020 semifinals. La Roja played to a 1-1 draw against Switzerland in the quarterfinals but advanced on penalty kicks, while the Italians reached this stage by posting a 2-1 victory over Belgium.

Kickoff from Wembley Stadium in London is scheduled for 3 p.m. ET. The latest Italy vs. Spain odds from William Hill Sportsbook list Italy as +140 favorites (risk $100 to win $140), while the over-under for total goals scored is 2.5. Before locking in any Spain vs. Italy picks, be sure to check out the Euro 2020 predictions from SportsLine's proprietary European soccer model.

Created by two Norwegians -- professional poker player and sports bettor Jonas Gjelstad, and economics and engineering expert Marius Norheim -- the model analyzes worldwide betting data and exploits market inefficiencies, helping its followers cash in. Since coming to SportsLine in 2019, the algorithm is up over $8,500.

Now, the model has set its sights on Spain vs. Italy at Euro 2020 and locked in its best bets. You can head to SportsLine now to see its picks. Here are the betting lines and trends for Italy vs. Spain:

  • Italy vs. Spain spread: Italy -0.5
  • Italy vs. Spain over-under: 2.5 goals
  • Italy vs. Spain money line: Italy +140, Spain +220, Draw +210
  • ITA: The Azzurri are unbeaten in their last 32 international matches (27 wins, five draws)
  • ESP: La Roja leads the tournament with 12 goals

Top Euro 2020 predictions for Spain vs. Italy

The model is leaning over 2.5 goals in Tuesday's matchup between Italy and Spain. There's no shortage of potential scorers on Italy's roster, as four players have recorded two goals in the tournament while five registered three or more during qualifying. Ciro Immobile and Lorenzo Insigne are on both lists, with each netting a trio of tallies in four qualifying games. Manuel Locatelli converted twice in a 3-0 triumph over Switzerland during group-stage action, while Matteo Pessina also has scored a pair of goals, including the game-winner versus Austria in the round of 16.

Spain is not far behind the Italians, as it has three players who enter Tuesday with two goals in the competition. To no one's surprise, one of them is Alvaro Morata, who also scored four times in six qualifying matches. The 28-year-old forward netted three tallies at Euro 2016 and is the only member of the squad with a double-digit goal total (21) during international play.

How to make Italy vs. Spain Euro 2020 picks

The model also has locked in a strong money line pick for Italy vs. Spain. You absolutely need to see it before you lock in your own Euro 2020 picks.

So who wins Spain vs. Italy? And where does all the betting value lie? Visit SportsLine now to find out which side of the Italy vs. Spain money line has all the value, all from the proprietary European soccer model that's up over $8,500.