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The second-ranked Purdue Boilermakers will look to re-establish their dominance over the Indiana Hoosiers when they meet in Big Ten action on Tuesday night. The Boilermakers (15-2, 4-2 Big Ten), who have won eight of their last nine games overall, have won 13 of the last 17 matchups with Indiana, but have lost three of the last four with the Hoosiers (12-5, 4-2 Big Ten). Indiana has won two of the last three games, including a 74-62 win over Minnesota on Friday. Purdue defeated Penn State 95-78 on Saturday, following an 88-72 loss at Nebraska on Jan. 9.

The game from Simon Skjodt Assembly Hall in Bloomington, Ind., starts at 7 p.m. ET. Purdue is averaging 85 points per game, while Indiana averages 74.4. The Boilermakers are 9.5-point favorites in the latest Purdue vs. Indiana odds from SportsLine consensus, while the over/under for total points scored is 150. Before making any Indiana vs. Purdue picks, be sure to see the college basketball predictions from SportsLine's proven model.

The model simulates every Division I college basketball game 10,000 times. It enters Week 11 of the 2023-24 season on a 110-73 roll on all top-rated college basketball picks dating back to last season, returning more than $2,000 for $100 players. It is also off to a sizzling 15-5 start on top-rated spread picks this season. Anyone following has seen huge returns.

The model has set its sights on Purdue vs. Indiana. You can head to SportsLine now to see the picks. Now here are the latest betting trends and lines for Indiana vs. Purdue:

  • Purdue vs. Indiana spread: Purdue -9.5
  • Purdue vs. Indiana over/under: 150 points
  • Purdue vs. Indiana money line: Purdue -491, Indiana +369
  • PUR: The Boilermakers have won 23 of their last 29 games (+9.90 units on ML)
  • IND: The Hoosiers have hit the game total over in 13 of their last 24 games at home (+0.90 units)
  • Purdue vs. Indiana picks: See picks at SportsLine

Why Purdue can cover

Senior center Zach Edey is looking to repeat as national player of the year and has been putting up big numbers again this season. He leads the Boilermakers, averaging a double-double with 22.3 points and 10.9 rebounds per game. In 17 starts this year, he has registered 10 double-doubles, and scored 30 or more points three times. In Saturday's win over Penn State, he connected on 10 of 12 shots and 10 of 14 free throws for 30 points, while grabbing 20 rebounds.

Also helping power Purdue is senior transfer guard Lance Jones. After four seasons at Southern Illinois, Jones has played in and started all 17 games for the Boilermakers in 2023-24. In 25.9 minutes per game, he is averaging 11.3 points, 2.5 assists and 2.5 rebounds. He has reached double-digit scoring in each of the last four games, including a 17-point performance in an 83-78 win at ninth-ranked Illinois on Jan. 5. See who to back at SportsLine.

Why Indiana can cover

The Hoosiers have four players scoring 10 points or more per game, led by sophomore forward Malik Reneau. He has started all 17 games for Indiana this season, averaging 16.3 points, 5.8 rebounds and 3.1 assists in 29.1 minutes of action. He is coming off a 16-point and six-rebound performance in Friday's win over Minnesota. He registered his only double-double of the year with a season-high 34 points and 11 rebounds in a 100-87 win over Kennesaw State on Dec. 29.

Sophomore center Kel'el Ware has been dominant of late. He has seven double-doubles on the year, including three in the last four games. In the win over Minnesota, he scored 17 points, while grabbing 14 rebounds. His highest scoring output was a 28-point effort in an 89-76 win over Harvard on Nov. 26. For the year, he is averaging 14.8 points, 9.6 rebounds, 1.8 assists and 1.6 blocks in 31.1 minutes of action. See who to back at SportsLine.

How to make Indiana vs. Purdue picks

The model has simulated this matchup 10,000 times and the results are in. The model is leaning Under the total, and it also says one side of the spread hits in well over 50% of simulations. You can only see the picks at SportsLine.

So who wins Purdue vs. Indiana, and which side of the spread hits well over 50% of the time? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that is on a 110-73 roll on its top-ranked college basketball picks, and find out.