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The Indiana Hoosiers refuse to lose at home this season as they are a stellar 11-0 on their own court. But the Purdue Boilermakers have established a winning streak in Bloomington, emerging victorious in each of their last five visits. One of the runs will come to an end Thursday as the fourth-ranked Boilermakers (15-2, 4-2 Big Ten) visit the Hoosiers (13-4, 4-3) for a Big Ten showdown. Indiana finished 6-6 at home in 2020-21 after losing its last two contests there, while Purdue posted an 81-69 victory in its trip to Bloomington last season.

Tipoff from Simon Skjodt Assembly Hall in Bloomington is set for 7 p.m. ET. The Boilermakers are 3.5-point favorites in the latest Purdue vs. Indiana odds at Caesars Sportsbook, while the over-under for total points scored is 140.5. Before making any Indiana vs. Purdue picks, you need to check out the college basketball predictions and betting advice from the SportsLine Projection Model

The model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of more than $2,400 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Purdue vs. Indiana, and just revealed its picks and CBB predictions. You can visit SportsLine now to see the model's picks. Here are the college basketball odds and trends for Indiana vs. Purdue:

  • Purdue vs. Indiana spread: Boilermakers -3.5
  • Purdue vs. Indiana over-under: 140.5 points
  • Purdue vs. Indiana: Boilermakers -170, Hoosiers +145
  • PUR: The Boilermakers are 3-7 against the spread in their last 10 games
  • IND: The Hoosiers are 8-0 ATS in their last eight home contests
Featured Game | Indiana Hoosiers vs. Purdue Boilermakers

Why Purdue can cover

The Boilermakers are one of the top offensive teams in the nation, ranking in the top 10 with an average of 86.2 points. Guard Jaden Ivey is scoring a team-high 16.4 points per game while fellow sophomore Zach Edey, a center, is contributing 15.6 along with 7.5 rebounds. Ivey was one of five players in double figures in Monday's 96-88 double-overtime triumph at No. 17 Illinois with 19 points and has produced 10 or more in 16 of his 17 games.

Edey poured in 20 points against the Fighting Illini, marking the fourth time in five outings he has reached that mark. Purdue has scored at least 90 points on a nation-best nine occasions this season and has done so in back-to-back conference games for the first time since February 1998. The Boilermakers have been receiving strong contributions from their reserves, who have amassed 25 or more points in 12 consecutive contests.

Why Indiana can cover

The Hoosiers have been outstanding at home this season, winning all 11 of their contests. Much of the success can be credited to their defensive play, as they rank first in the Big Ten in field-goal percentage defense (36.5) and scoring defense (62.7). Trayce Jackson-Davis leads Indiana in both scoring and rebounding as he is averaging 19.5 points and 9.1 boards per contest.

The redshirt sophomore forward notched 23 points on 10-of-16 shooting and pulled down 12 rebounds in the Hoosiers' 78-71 victory at Nebraska on Monday for his fourth consecutive double-double and eighth overall this season. During the streak, Jackson-Davis is averaging 20.3 points and 11.8 boards while shooting 63.5 percent from the floor. Junior forward Race Thompson reached double digits in points for the 10th time in 11 games with 12 against the Cornhuskers while freshman forward Jordan Geronimo, who is averaging just 4.5 points, came off the bench to record 10 and grab eight rebounds.

How to make Indiana vs. Purdue picks

SportsLine's model is leaning over on the total, projecting the teams to combine for 143 points. It also says one side of the spread is hitting in well over 50 percent of the time. You can only get the model's pick at SportsLine.

So who wins Purdue vs. Indiana? And which side of the spread cashes in well over 50 percent of simulations? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up more than $2,200 on its top-rated college basketball spread picks over the last five-plus years, and find out.