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Get ready for an ACC battle on Wednesday as the Notre Dame Fighting Irish and the No. 20 Virginia Tech Hokies will face off at 7 p.m. ET at Purcell Pavilion at the Joyce Center. Notre Dame is 5-8 overall and 3-3 at home, while the Hokies are 11-3 overall and 1-2 on the road. The Hokies are 7-2-1 against the spread in their last 10 road games against a team with a losing home record. The Fighting Irish are 1-4 against the spread in their last five home games. 

The road team is 8-3 against the spread in the last 11 meetings between these two teams. The game is a pick 'em in the latest Notre Dame vs. Virginia Tech odds from William Hill Sportsbook, and the over-under is set at 139.5. Before entering any Virginia Tech vs. Notre Dame picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of almost $2,300 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Notre Dame vs. Virginia Tech. You can head to SportsLine to see its picks. Here are several college basketball odds for Notre Dame vs. Virginia Tech:

  • Notre Dame vs. Virginia Tech spread: Pick 'Em
  • Notre Dame vs. Virginia Tech over-under: 139.5 points
  • Notre Dame vs. Virginia Tech money line: Notre Dame -110, Virginia Tech -110

What you need to know about Notre Dame

The Fighting Irish won their second straight game Sunday, downing Miami 73-59. Juwan Durham was out in front, picking up 16 points along with five rebounds. For the season, Durham is averaging 8.8 points, 5.2 rebounds and 1.5 assists per game. 

Nate Laszewski leads Notre Dame in both scoring, at 16.6 points per game, and rebounding at 7.8 boards per contest. Prentiss Hubb dishes a team-high 5.3 assists per outing.

What you need to know about Virginia Tech

The Hokies saw a three-game winning streak snapped on Saturday when they fell 78-60 to Syracuse. Despite the defeat, Virginia Tech got a solid performance out of guard Nahiem Alleyne, who shot 5-for-10 from beyond the arc and finished with 20 points.

Virginia Tech thumped Notre Dame 77-63 earlier in January. Keve Aluma leads the Hokies in scoring (13.9 points per game) and rebounding (7.1 rebounds per game), while Wabissa Bede dishes a team-high 2.6 assists per outing.

How to make Virginia Tech vs. Notre Dame picks

The model has simulated Notre Dame vs. Virginia Tech 10,000 times and the results are in. We can tell you that the model is leaning over, and it also says one side of the spread hits in over 50 percent in simulations. You can only see the pick at SportsLine.

So who wins Notre Dame vs. Virginia Tech? And which side of the spread cashes in over 50 percent of simulations? Visit SportsLine now to find out which side of the Virginia Tech vs. Notre Dame spread you need to jump on Wednesday, all from the model that has crushed its college basketball picks, and find out.