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The No. 10 LSU Tigers will try to spring a big upset when they face the No. 6 Alabama Crimson Tide on Saturday night. LSU has won six of its last seven games, including consecutive double-digit wins over Florida and then-No. 7 Ole Miss. Alabama bounced back from a loss at Tennessee with a 30-6 win against then-No. 24 Mississippi State in its last game before having an open date last week.

Kickoff is set for 7 p.m. ET. The Crimson Tide are 13.5-point favorites in the latest LSU vs. Alabama odds from Caesars Sportsbook, while the over/under for total points scored is 56.5. Before entering any Alabama vs. LSU picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on LSU vs. Alabama. You can head to SportsLine to see its picks. Here are several college football odds for Alabama vs. LSU:

  • Alabama vs. LSU spread: Alabama -13.5
  • Alabama vs. LSU over/under: 56.5 points
  • Alabama vs. LSU money line: LSU +400, Alabama -550
  • Alabama vs. LSU picks: See picks here

Why LSU can cover

Alabama has had some shaky outings on the road this season, squeaking past Texas in a 20-19 final as a 21-point favorite. The Crimson Tide also lost at Tennessee several weeks ago, so they have not proven that they are worth backing in big road games. They have only covered the spread two times in their last seven games away from home dating back to last season.

LSU has won six of its last seven games, with its lone loss coming against the Vols in early October. The Tigers have exploded offensively in their last two games, scoring a combined 90 points in wins over Florida and Ole Miss. Quarterback Jayden Daniels has run for six touchdowns and passed for five in those two games, and he has already set a school record for rushing touchdowns in a season (9) for a quarterback. Alabama has historically struggled against mobile quarterbacks, making this spread look too large. 

Why Alabama can cover

Alabama tends to put together strong performances in big games under head coach Nick Saban. The Crimson Tide have dominated good LSU teams over the past decade, and the Tigers have already been blown out by Tennessee at home this season. Alabama is led by star quarterback Bryce Young, who has thrown for 1,906 yards and 18 touchdowns while rushing for another three scores.

Junior running back Jahmyr Gibbs has turned into one of the top running backs in the country, rushing for 672 yards and six touchdowns, averaging 6.9 yards per carry. LSU has yet to score first in an SEC game, which does not bode well against Alabama. The Tigers are winless in their last five home games against the Crimson Tide and are not prepared to compete on Saturday night. 

How to make Alabama vs. LSU picks

The model has simulated LSU vs. Alabama 10,000 times and the results are in. The model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 60% of simulations. You can only see the pick at SportsLine.

So who wins Alabama vs. LSU? And which side of the spread hits in almost 60% of simulations? Visit SportsLine now to see which side of the LSU vs. Alabama spread you need to jump on Saturday, all from the model that has crushed its college football picks, and find out.