Eastern Michigan makes a rare trip out west to take on Arizona State this Saturday night at Sun Devil Stadium, Frank Kush Field in Tempe, AZ. This is the schools' first meeting in football. Eastern Michigan has only faced one other Pac-12 team in its history; they fell 55-0 to ASU's rival, Arizona, in 1988. The Eagles are 1-1 this season after being trounced on the road by Louisiana, 49-21 in Week 2. Similarly, the Sun Devils are 1-1 after a 34-17 defeat at the hands of then No. 11 Oklahoma State

Kickoff is set for 11:00 p.m. ET. The Sun Devils are favored by 20 points in the latest Arizona State vs. Eastern Michigan odds from Caesars Sportsbook, and the over/under is set at 56.5. Before making any Eastern Michigan vs. Arizona State picks, you'll need to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,400 for $100 players on its top-rated college football picks against the spread. It enters Week 3 of the 2022 college football season on a 50-41 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Arizona State vs. Eastern Michigan and just locked in its CFB picks. You can head to SportsLine to see its picks. Here are several college football odds for Arizona State vs. Eastern Michigan:

  • Arizona State vs. Eastern Michigan spread: Arizona State -20
  • Arizona State vs. Eastern Michigan over/under: 56.5 points
  • Arizona State vs. Eastern Michigan picks: See picks here
Latest Odds: Arizona State Sun Devils -20.5

What you need to know about Eastern Michigan

After a close 42-34 win over FCS Eastern Kentucky in Week 1, the Eagles were stomped by Louisiana last Saturday. The team had five turnovers in the loss, including three interceptions by QB Taylor Powell. Despite throwing for 317 yards and a score, Powell was also sacked four times. After rushing as a team for 124 yards against EKU, the Eagles were held to only 41 yards on 23 carries vs. the Ragin' Cajuns. 

Running back Samson Evans has rushed for two touchdowns on the season and threw for one in last weekend's game. Wide receiver Tanner Knue has caught 12 passes for 132 yards and three scores in the team's two games. Defensively, EMU has only one quarterback sack and has forced two turnovers thus far in 2022.

What you need to know about Arizona State

ASU hung with Oklahoma State until midway through the fourth quarter, only trailing by three points after an Emory Jones touchdown pass to Elijhah Badger early in the period. The Cowboys scored twice more to account for the 17-point difference. Senior running back Xazavian Valladay, a transfer from Wyoming, has been a bright spot for the Sun Devils rushing for 234 yards and three scores in the team's first two games.

Florida transfer QB Emory Jones has only thrown for the one touchdown on the season but rushed for two more in the team's Week 1 lopsided 40-3 win over FCS Northern Arizona. On defense, senior linebacker Kyle Soelle leads the team with 21 tackles and two interceptions.

How to make Arizona State vs. Eastern Michigan picks

The model has simulated Arizona State vs. Eastern Michigan 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 70% of simulations. You can only see the model's pick at SportsLine.

So who wins the matchup between Arizona State and Eastern Michigan? And which side of the spread hits almost 70% of the time? Visit SportsLine now to see which side of the ASU vs. EMU spread to jump on, all from the advanced model that finished the past six-plus years up nearly $3,400 on its FBS college football picks, and find out.