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College football fans received an appetizer last weekend and on Thursday and Friday night, but the main course is coming up on Saturday. No. 3 Clemson takes on No. 5 Georgia in Charlotte in a game where Caesars Sportsbook has made Clemson a three-point favorite. The college football schedule also includes No. 17 Indiana vs. No. 18 Iowa and No. 1 Alabama vs. No. 14 Miami (FL).

The Hawkeyes are listed as four-point favorites against the Hoosiers in what might wind up being one of the more entertaining games of the day. Alabama is expected to take care of business -- Caesars has the Crimson Tide priced as 19.5-point favorites. Before locking any college football bets for those games or others be sure to see the top Week 1 college football expert picks, predictions and best bets from Barrett Sallee.

Sallee is a true insider -- a CBS Sports analyst, SiriusXM host, Heisman voter and consistently one of the top CBS Sports experts picking games against the spread -- and his best bets have helped bring in huge returns. He debuted with SportsLine in 2017 and has delivered in a big way on his college football picks

Over the past two-plus years, he is 82-55 in his popular best bets column at SportsLine, including going 3-0 to start the 2021 season. Anybody who has been following him is way up.

Now, he has turned his attention to the Week 1 college football odds from Caesars and is sharing his top three best bets over at SportsLine. If you parlay them together, you could be looking at a return of around 6-1. Get his top college football picks now

Top Week 1 college football expert predictions

One of Sallee's top college football picks for Week 1: He likes the over (58) in the Texas vs. Louisiana matchup on Saturday at 4:30 p.m. ET.

Louisiana's offense is led by fifth-year senior quarterback Levi Lewis, who has a 54-14 touchdown-to-interception ratio during his career. He has five returning offensive linemen in front of him and the entire wide receiver corps is back.

Texas fans are excited for its new offense under first-year head coach Steve Sarkisian. His high-powered attack is going to be run through junior quarterback Casey Thompson, who was sharp in his Alamo Bowl performance to close the 2020 season.

The Longhorns also return running back Bijan Robinson, who is excellent in the rushing attack and passing game. Texas has gone over the total in seven of its last 10 games. 

Featured Game | Texas Longhorns vs. Louisiana Ragin' Cajuns

How to make Week 1 college football picks 

Sallee has also found two other college football picks he's high on, including backing an underdog in a game where he says "the wrong team is favored." You can only see his picks at SportsLine.

What are the best bets for Week 1 of college football? And which line does Sallee believe is flipped? Visit SportsLine now to see Barrett Sallee's college football best bets, all from one of the top analysts in the nation who has crushed his picks for SportsLine.