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The No. 1 Georgia Bulldogs and South Carolina Gamecocks take the field for their 75th all-time meeting on Saturday. South Carolina hosts the proceedings at Williams-Brice Stadium in Columbia. Georgia sits atop college football following a 2021 national title, and the Bulldogs are 2-0 to begin this season. South Carolina is 1-1 on the heels of a 14-point loss to Arkansas, and the Gamecocks are led by Shane Beamer.

Caesars Sportsbook lists Georgia as a 25-point favorite on the road for this noon ET kickoff. The total number of points Vegas thinks will be scored, or the over/under, is 55 in the latest Georgia vs. South Carolina odds. Before making any South Carolina vs. Georgia picks, you need to see the college football predictions and betting advice from SportsLine's advanced computer simulation model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,400 for $100 players on its top-rated college football picks against the spread. It enters Week 3 of the 2022 college football season on a 50-41 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Georgia vs. South Carolina and just locked in its picks and CFB predictions. You can head to SportsLine now to see the model's picks. Now, here are several college football odds and betting lines for South Carolina vs. Georgia: 

  • Georgia vs. South Carolina spread: Georgia -25
  • Georgia vs. South Carolina over/under: 55 points
  • Georgia vs. South Carolina money line: Georgia -4000, South Carolina +1450
  • UGA: The Bulldogs are 11-6 against the spread in the last 17 games
  • SC: The Gamecocks are 7-7-1 against the spread in the last 15 games
  • Georgia vs. South Carolina picks: See picks at SportsLine

Why Georgia can cover

Georgia has 13 consecutive road wins against SEC East opponents, and the Bulldogs enter the week at No. 1 in the country. Kirby Smart's team is 53-19-2 all-time against South Carolina, including a 6-1 mark in the last seven games. Georgia hasn't lost to South Carolina in Columbia since 2014, with the Gamecocks scoring 20 points or fewer in the last seven matchups. Georgia has dominated the competition to this point, throttling Oregon and blanking Samford last week in the ninth shutout of the Kirby Smart era. 

The Bulldogs held Samford to 128 total yards and 19 yards on the ground, and Georgia thoroughly manhandled a talented Oregon team at a semi-neutral site in Atlanta. Georgia's defense is tremendous once again, but the Bulldogs are firing on offense as well, scoring on the first six drives in both games this season. Georgia is No. 1 among SEC teams in averaging 525 total yards per game this season, and the Bulldogs are averaging 41 points per game. The Bulldogs are lighting it up through the air with 395 passing yards per game, and Georgia is generating 9.9 yards per pass attempt with only one sack allowed.

Why South Carolina can cover

South Carolina brought in a lot of talent and experience at quarterback in the offseason. Spencer Rattler, a former five-star prospect, transferred from Oklahoma, where he threw for more than 4,500 yards and 40 touchdowns for the Sooners. Rattler has 603 passing yards in two games at South Carolina, averaging 7.9 yards per pass attempt this season. 

On the outside, South Carolina has a standout in Antwane Wells Jr., who transferred from James Madison, and Wells caught eight passes for 189 yards and a touchdown against Arkansas. The Gamecocks are also playing frisky defense against the pass this season. South Carolina is allowing only 136.5 passing yards per game, No. 2 among SEC teams in 2022, and opponents are completing only 50% of their pass attempts against the Gamecocks. South Carolina is also holding the opposition to 5.5 yards per attempt through three games.

How to make South Carolina vs. Georgia picks

SportsLine's model is leaning Under on the total, projecting 48 combined points. The model also says one side of the spread hits in more than 60% of simulations. You can only see the model's pick at SportsLine

So who wins Georgia vs. South Carolina? And which side of the spread hits in more than 60% of simulations? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.