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Teams eyeing improvement clash in the 2023 Aflac Kickoff Game when the Louisville Cardinals take on the Georgia Tech Yellow Jackets in an ACC and season opener on Friday. It will be just the third all-time meeting between the schools. Georgia Tech has posted wins in each of the two previous meetings, including a 46-27 win in their last matchup on Oct. 9, 2020, in Atlanta. This will be Louisville coach Jeff Brohm's debut after spending the previous six years at Purdue, where he posted a 36-34 mark and guided the Boilermakers to the Big Ten Conference West Division title in 2022. Brohm played quarterback at Louisville from 1989-93. 

The game from Mercedes-Benz Stadium in Atlanta is set to kick off at 7:30 p.m. ET. Louisville's defense allowed 330.2 yards per game last year, while Georgia Tech's allowed 401. The Cardinals are favored by 7.5 points in the latest Louisville vs. Georgia Tech odds, while the over-under for total points scored is 49.5. Before making any Georgia Tech vs. Louisville picks, be sure to check out the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, the proprietary computer model has generated a stunning profit of almost $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Georgia Tech vs. Louisville and just revealed its picks and predictions. You can visit SportsLine now to see the model's CFB picks. Here are several college football odds and trends for Louisville vs. Georgia Tech:

  • Louisville vs. Georgia Tech spread: Louisville -7.5
  • Louisville vs. Georgia Tech over/under: 49.5 points
  • Louisville vs. Georgia Tech money line: Louisville -297, Georgia Tech +238
  • LOU: The Cardinals have gone under the game total in their last five games
  • GT: The Yellow Jackets have gone under the game total in each of their last four games at home
  • Louisville vs. Georgia Tech picks: See picks at SportsLine

Why Louisville can cover

Junior running back Jawhar Jordan looks to take over as the Cardinals featured back for the entire season after taking over those duties midway through last season. Jordan rushed for a career-best 815 yards and four touchdowns, bettering his previous career high of 105 yards during the 2019 season. Once he took over the featured back duties in 2022, he wasted little time showing off his explosiveness. He totaled four 100-yard rushing games, each coming in the final five games. He rushed for 117 yards in a win over James Madison, 105 against North Carolina State, 145 at Kentucky and 115 against Cincinnati in the Fenway Bowl.

On defense, the Cardinals return three players who started every game last season and three others who started at least four or more, for a unit that allowed just 19.2 points, the fewest since 2013. On the defensive line, Ashton Gillotte and Dezmond Tell combined to start 25 games last season. Gillotte recorded seven sacks, and made 23 stops, including 12 solo, with one pass breakup, one forced fumble and two fumble recoveries. Tell had two sacks and one fumble recovery, while making 26 tackles, including 10 solo. See which team to pick here

Why Georgia Tech can cover

Among the Yellow Jackets' top returners include senior running back Dontae Smith. He was the team's second-leading rusher a year ago, carrying 87 times for 420 yards (4.8 average) and five touchdowns. In his previous four seasons at Georgia Tech, Smith has rushed 208 times for 1,159 yards (5.6 average) and 12 touchdowns. He also has 34 receptions for 223 yards (6.6 average). His best game last season was an 11-carry, 102-yard and three-touchdown effort against Western Carolina in a 35-17 win.

Sophomore wide receiver Malik Rutherford also returns after finishing with 23 receptions for 225 yards (9.8 average), fourth-best on the team. In two previous seasons with the Yellow Jackets, he has 28 receptions for 287 yards (10.3 average), including a long of 38 yards. His best game last season was a six-catch, 68-yard effort in a 21-17 victory at No. 13 North Carolina. He also had four receptions for 52 yards in a 42-0 loss to No. 20 Ole MissSee which team to pick here.

How to make Georgia Tech vs. Louisville picks

SportsLine's model is leaning Under on the point total, projecting the teams to combine for 48 points. The model also says one side of the spread hits 60% of the time. You can only see the model picks at SportsLine.

So who wins Louisville vs. Georgia Tech, and which side of the spread hits 60% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has notched a profit of almost $2,500 on its top-rated college football spread picks, and find out.