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After a couple of the PGA Tour's weaker events of the season, things really ramp up this week with the 2022 FedEx St. Jude Championship in Memphis. Tenn. It is the first event of the PGA Tour's FedExCup Playoffs, and TPC Southwind should be a tough initial test. The course plays longer than advertised, and the narrow fairways, doglegs and water hazards will separate the contenders from the pretenders. Scottie Scheffler sits atop the FedExCup standings – and the world rankings – but the Masters champ's lead isn't safe. He has a 1,220-point lead over second-place Cameron Smith, but this week's winner earns 2,000 points. That means Smith and the rest of the top five – Sam Burns, Xander Schauffele and reigning FedExCup champ Patrick Cantlay – have a good chance. Rory McIlroy, Justin Thomas, Jon Rahm and Jordan Spieth are among the many stars who also could make a big move with a victory. The top 125 players in the standings qualified, and the field will be pared down to 30 over the next two weeks. The FedExCup and the $18 million final prize will be awarded after the Tour Championship, set for Aug. 25-28 at East Lake in Atlanta.         

There are eight golfers priced at 20-1 or shorter in the latest 2022 FedEx St. Jude Championship odds from Caesars Sportsbook. McIlroy is the 10-1 favorite, followed by Scheffler (14-1) and Smith (16-1). Cantlay (18-1), Rahm (18-1), Thomas (18-1) and Schauffele (18-1) also are top contenders. Tony Finau, who has won his last two tournaments, is 20-1, while Burns is 25-1 and Spieth is in a group at 28-1. Before locking in any 2022 FedEx St. Jude Championship picks, you need to check out the FedEx St. Jude Championship 2022 predictions and best bets from golf insider Patrick McDonald.

After spending time at FanSided and NBC Sports EDGE, McDonald joined CBS Sports as a golf writer in the spring of 2022. Now covering the sport from a broader perspective, McDonald still likes to dip his toes into the betting pools on a weekly basis on the PGA Tour. 

McDonald took a risk last week at the Wyndham Championship in fading Sedgefield Country Club ace Webb Simpson, who had nine top-10's in 13 appearances. Simpson had a rough week and was 2-over and headed for a missed cut before he withdrew.     

McDonald just missed on his longshot play at the Rocket Mortgage Classic, with 80-1 shot Taylor Pendrith battling for the lead all week until winner Tony Finau's dominant Sunday. He also pegged Pendrith as the first-round leader at 70-1, and the Canadian shared that honor with Finau.

Now, McDonald has studied the 2022 FedEx St. Jude Championship field and is locking in his best bets, top sleepers and favorites to avoid. You can head to SportsLine now to see all of his 2022 FedEx St. Jude Championship picks and predictions.

Top 2022 FedEx St. Jude Championship expert picks

One shocking prediction from McDonald: Burns might not even make the cut after finishing as a runner-up last season. Burns shot 16 under par, including a pair of 64's, before losing in a playoff to Abraham Ancer in the 2021 WGC event. But he hasn't finished in the top 20 since June, and the hot putter that carried him last year – he was second in the field in strokes gained – is unlikely to return. "This number does not make much sense," the expert says of the 25-1 odds.

On the other hand, Sungjae Im is one player McDonald really recommends you back this week, especially at 35-1. The South Korean has gone 29 under par over his last two tournaments, finishing as a runner-up in both. He ranks ninth on tour in total strokes gained and fourth in scrambling. The combination of his strong play around the green and his long iron work (25th on approaches over 200 yards) make this course a perfect fit for the state of his game right now. See who else to pick at the FedEx St. Jude Championship here.

How to make 2022 FedEx St. Jude Championship golf picks

Before this week's PGA Tour event in Memphis, McDonald has locked in his best bets for the 2022 FedEx St. Jude Championship. They include a longshot who comes in at massive triple-digit odds. This golfer is at his best with an iron in his hand and knows leaving his unpredictable driver in the bag is his best chance to pull off a shocking win. You can find out who it is, and see the rest of McDonald's FedEx Cup Playoff picks, over at SportsLine.

So which 2022 FedEx St. Jude Championship picks should you target? Where does all the betting value lie for FedEx St. Jude Championship 2022? Check out the odds below, then visit SportsLine to see Patrick McDonald's top prop picks for FedEx St. Jude Championship 2022, all from the expert who's up more than 52 units on outright plays in 2022, and find out.

2022 FedEx St. Jude Championship odds, field

See full FedEx St. Jude Championship 2022 picks, best bets, and predictions here

Rory McIlroy +1100
Scottie Scheffler +1400
Cameron Smith  +1600
Jon Rahm +1600
Justin Thomas +1600
Xander Schauffele  +1600
Patrick Cantlay +1600
Matt Fitzpatrick +2000
Tony Finau +2000
Sam Burns +2200
Collin Morikawa +2500
Jordan Spieth +2500
Will Zalatoris +2500
Cameron Young +2500
Viktor Hovland +3000
Hideki Matsuyama +3500
Sungjae Im +3500
Shane Lowry +3500
Billy Horschel +4000
Joohyung Kim +4500
Joaquin Niemann +5000
Max Homa +5000
Tyrrell Hatton +5500
Russell Henley +5500
Aaron Wise +6000
Corey Conners +6500
Davis Riley +7500
Taylor Pendrith +7500
Seamus Power +8000
Alex Noren +8000
Sahith Theegala +9000
Cam Davis +9000
Webb Simpson +9000
Harold Varner III +10000
Adam Scott +10000
Christiaan Bezuidenhout +10000
Adam Hadwin +10000
Scott Stallings +10000
Keith Mitchell +10000
J.T. Poston +10000
Mito Pereira +10000
Denny McCarthy +10000
Si Woo Kim +10000
Keegan Bradley +10000
Cameron Tringale +12500
Justin Rose +12500
Gary Woodland +12500
Chris Kirk +12500
Brian Harman +12500
Marc Leishman +15000
Matt Kuchar +15000
Maverick McNealy +15000
Jason Day +15000
Lucas Herbert +15000
Adam Long +15000
Alex Smalley +15000
Brendan Steele +15000
Wyndham Clark +17500
Emiliano Grillo +17500
Sebastian Munoz +17500
Tom Hoge +17500
Kevin Kisner +17500
Chez Reavie +17500
Taylor Moore +17500
Anirban Lahiri +20000
Brendon Todd +20000
Jhonattan Vegas +20000
Lee Hodges +20000
Stewart Cink +22500
Luke List +22500
Aaron Rai +22500
Mark Hubbard +22500
Kevin Streelman +22500
K.H. Lee +22500
Kurt Kitayama +22500
Brandon Wu +22500
Callum Tarren +22500
Matthew NeSmith +25000
John Huh +25000
Russell Knox +27500
Adam Svensson +27500
Troy Merritt +27500
Ryan Palmer +30000
J.J. Spaun +30000
Stephan Jaeger +30000
Martin Laird +30000
C.T. Pan +30000
Trey Mullinax +30000
Andrew Putnam +35000
Chesson Hadley +35000
Doug Ghim +40000
Beau Hossler +40000
Danny Lee +40000
Nate Lashley +40000
Hayden Buckley +40000
David Lipsky +40000
Peter Malnati +40000
Rickie Fowler +40000
Greyson Sigg +40000
Dylan Frittelli +40000
Joel Dahmen +40000
Patrick Rodgers +40000
Tyler Duncan +40000
Michael Thompson +50000
James Hahn +50000
Vince Whaley +50000
Adam Schenk +50000
Mackenzie Hughes +50000
Sam Ryder +50000
Scott Piercy +50000
Chad Ramey +50000
Sepp Straka +50000