Comerica Park hosts afternoon baseball between division rivals on Thursday. The Detroit Tigers welcome the Minnesota Twins to town for the final game of a five-game set this week. Minnesota is 30-22 overall this season, though Detroit has won three of the first four games in the series. The Tigers are 6-2 in the last eight games, improving to 20-30 in 2022.

Caesars Sportsbook lists the Twins as -130 money line favorites, and first pitch is scheduled for 1:10 p.m. ET. The total number of runs Vegas thinks will be scored, or the Over-Under, is 8.5 in the latest Tigers vs. Twins odds. Before you make any MLB predictions with the Twins vs. Tigers match-up, you need to see the MLB predictions and betting advice from SportsLine's advanced computer simulation model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It's on a 48-31 roll on top-rated MLB money-line picks through eight weeks, returning over $1,100 for $100 players. Anyone following it has seen huge returns.

Now, the model has set its sights on Twins vs. Tigers and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Now, here are several MLB odds and betting lines and trends for Tigers vs. Twins:

  • Twins vs. Tigers money line: Twins -130, Tigers +110
  • Twins vs. Tigers over-under: 8.5 runs 
  • Twins vs. Tigers run line: Twins -1.5 (+140)
  • Twins vs. Tigers tickets: See tickets at StubHub
  • MINN: The Twins are 13-11 in road games 
  • DET: The Tigers are 14-15 in home games
Featured Game | Detroit Tigers vs. Minnesota Twins

Why you should back the Twins

Minnesota has the superior offense in this matchup by a considerable margin. The Twins lead the American League with a .322 on-base percentage, and Minnesota has 222 runs scored this season. That ranks in the top five of the AL, with top-tier marks in walk rate (9.4 percent), batting average (.245), slugging percentage (.392), and doubles (87).

To this point in the 2022 season, Detroit has been the worst offensive team in the AL, scoring only 143 runs. That is the fewest in the league, and the Tigers are also dead-last in home runs and slugging percentage. Detroit ranks in the bottom three of the league in batting average, on-base percentage, stolen bases, and walk rate, and Minnesota has an experienced starting pitcher in Chris Archer. He allowed only one run against Detroit on May 23, and Archer has a 3.31 ERA in road games this season to go along with a career 3.57 ERA against the Tigers.

Why you should back the Tigers

Detroit's run prevention is stellar. The Tigers are in the top three of the American League in team ERA at 3.48, and Detroit's bullpen is genuinely strong. Detroit's relievers are No. 2 in the AL with a 2.88 combined ERA, and the Tigers are near the top of the league in wins above replacement and ground ball rate (47.2 percent) from relief pitchers. Minnesota has offensive strengths, but the Twins are dead-last in the American League with only 10 stolen bases. 

On the other side, Detroit is facing a struggling starter in Archer, who has a 4.93 ERA in his last 38 outings overall. In contrast, the Tigers are deploying a former first-round pick in Alex Faedo, who has a 3.00 ERA this season with less than three walks per nine innings and two earned runs or fewer allowed in each outing in 2022.

How to make Twins vs. Tigers picks

SportsLine's model is leaning under on the run total, and it says one side of the money line has all the value. You can only get the model's MLB picks at SportsLine.

So who wins Twins vs. Tigers? And which side has all the value? Visit SportsLine now to see which side of Twins vs. Tigers you need to jump on Thursday, all from the model that has crushed its MLB picks, and find out.