It's an Eastern Conference battle when the Cleveland Cavaliers host the New York Knicks in the first tipoff on the Monday NBA schedule. The Knicks (23-24) sit in 11th place in the NBA Eastern Conference standings as they fight to get in playoff position. The Cavs (28-19) are in fifth place, just two games out of first in a tightly-packed bunch. Lauri Markkanen (ankle) has been ruled out for the Cavs. Derrick Rose (ankle) remains out for New York, while Mitchell Robinson (ankle) and Kemba Walker (knee) are day-to-day.

Tipoff is set for 7 p.m. ET at Rocket Mortgage FieldHouse. Caesars Sportsbook lists Cleveland as the six-point home favorite in the latest Knicks vs. Cavaliers odds. The over-under for total points is set at 203. Before locking in any Cavaliers vs. Knicks picks, be sure to see the NBA predictions and betting advice from SportsLine's proven computer model

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model enters Week 15 of the 2021-22 NBA season on a stunning 58-32 roll on all top-rated NBA picks, returning over $2,100. Anyone following it has seen huge returns.

Now, the model has set its sights on Knicks vs. Cavs, and just locked in its picks and NBA predictions. You can head to SportsLine now to see the model's picks. Here are several NBA betting lines and trends for Cavs vs. Knicks:

  • Knicks vs. Cavaliers spread: Cavaliers -6
  • Knicks vs. Cavaliers over-under: 203 points
  • NYK: The Knicks are 5-2 against the spread in the last seven games
  • CLE: The Cavaliers are 3-2-1 against the spread in the last six games
Featured Game | Cleveland Cavaliers vs. New York Knicks

Why the Knicks can cover

New York is very potent on the offensive glass, securing nearly 29 percent of available rebounds. The Knicks are in the top 10 of the NBA in second-chance points as a result, and New York ranks in the top 10 in 3-pointers and 3-point accuracy. New York is above-average in free-throw creation and turnover prevention, further bolstering the team's profile. On defense, the Knicks are allowing 1.09 points per possession, and New York is No. 2 in the NBA in points in the paint allowed. 

New York is in the top five in field-goal percentage allowed and 2-point percentage allowed, with top-10 marks in free-throw attempts allowed and defensive rebound rate. Cleveland has few weaknesses, but the Cavaliers are just No. 27 in the NBA in avoiding turnovers, committing more than 15 per contest.

Why the Cavaliers can cover

The Cavs, winners of seven of their last eight games, have been one of the best bets in the NBA this season, going 29-16-2 against the spread overall. The percentage jumps even higher in Cleveland, where the Cavs are 14-7-1 ATS. Cleveland already beat the Knicks 126-109 in New York this season, easily covering as 7.5-point underdogs in that Nov. 7 matchup.

Cleveland has overcome the loss of Collin Sexton (knee) for the year thanks in large part to several other emerging talents. Darius Garland is averaging 19.8 points, 8.1 assists and 1.2 assists per game. Center Jarrett Allen (16.3 ppg, 11 rpg) and forward Evan Mobley (15 ppg, 8.1 rpg) form one of the better young post duos in the NBA. 

How to make Cavaliers vs. Knicks picks

SportsLine's model is leaning over on the total, projecting 206 total points. The model also says one side of the spread hits well over 50 percent of the time. You can only see the model's pick at SportsLine.

So who wins Knicks vs. Cavs? And which side of the spread hits well over 50 percent of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its NBA picks, and find out.