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The Boston Celtics and the New York Knicks will face off in an Atlantic Division clash at 7:30 p.m. ET on Wednesday at TD Garden. Both teams are 25-26; Boston is 15-10 at home, while New York is 11-16 on the road. The teams are tied at seventh in the Eastern Conference and both are two games behind the fourth seed. 

Boston is favored by three-points in the latest Celtics vs. Knicks odds from William Hill Sportsbook, and the over-under is set at 209. Before entering any Knicks vs. Celtics picks, you'll want to see the NBA predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times, and it has returned almost $8,900 in profit on its top-rated NBA picks over the past two-plus seasons. The model is up almost $900 on its top-rated picks this season, and dating back to last year, it entered Week 16 of the 2020-21 NBA schedule on a stunning 93-59 roll on top-rated NBA picks against the spread. Anybody who has followed it has seen huge returns.

Now, the model has set its sights on Celtics vs. Knicks. You can head to SportsLine to see its picks. Here are several NBA betting lines for Celtics vs. Knicks:

  • Celtics vs. Knicks spread: Celtics -3
  • Celtics vs. Knicks over-under: 209 points
  • Celtics vs. Knicks money line: Boston -150, New York +130  

What you need to know about the Celtics

The Celtics lost to the Philadelphia 76ers on Tuesday, 106-96. Jayson Tatum (20 points) was the top scorer for Boston. The Celtics have lost nine of their past 15 games. They failed in a bid to win a third consecutive game on Tuesday. 

The Celtics committed 22 turnovers and trailed by as many as 21 points against the Sixers. Kemba Walker will be rested and won't play against the Knicks on Wednesday. Evan Fournier and Tristan Thompson are out due to health and safety protocols. 

What you need to know about the Knicks

The Knicks came up short against the Nets on Monday, 114-112. Julius Randle posted a triple-double with 19 points, 15 boards, and 12 assists, while Reggie Bullock shot 5-for-10 from beyond the arc and finished with 21 points. The Knicks have lost four of their past five games. 

The Knicks were ahead by 14 at halftime against the Nets but could not hold onto their lead. Randle has four triple-doubles this season. The Knicks won the first meeting with the Celtics earlier this year, 105-75 on Jan. 17. 

How to make Knicks vs. Celtics picks

The model has simulated Celtics vs. Knicks 10,000 times and the results are in. We can tell you that the model is leaning under, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Celtics vs. Knicks? And which side of the spread hits in over 60 percent of simulations? Visit SportsLine now to see which side of the Celtics vs. Knicks spread to jump on Wednesday, all from the model that is on an incredible 93-59 roll.