The San Antonio Spurs and the Memphis Grizzlies are set to square off in a Southwest Division matchup at 8 p.m. ET on Friday at FedExForum. Memphis is 16-22 overall and 8-12 at home, while San Antonio is 16-20 overall and 5-11 on the road. The Grizzlies enter Friday's contest on a three game win streak. San Antonio, meanwhile, has won four of its last six. The latest Grizzlies vs. Spurs odds see this game as a pick 'em, while the over-under is set at 231. Before entering any Spurs vs. Grizzlies picks, you'll want to see the NBA predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times, and last season it returned a whopping $4,280 on its top-rated NBA spread and money line picks. It's already returned almost $1,800 in profit on all its top-rated NBA picks during the 2019-20 season and entered Week 11 on a blistering 26-13 run on all top-rated NBA spread picks. Anybody who has followed it has seen huge returns.

Now, it has simulated Grizzlies vs. Spurs 10,000 times and the results are in. We can tell you that the model is leaning under, and it's also generated a spread pick that is hitting in well over 50 percent of simulations. You can only see the pick at SportsLine.

Memphis was able to grind out a solid victory over Minnesota on Tuesday, winning 119-112. The Grizzlies' success was the result of a balanced attack that saw several players step up, but Jae Crowder led the charge as he had 14 points along with eight boards and five steals. Rookie Ja Morant also had a strong showing against Minnesota, finishing with 25 points, seven assists and four rebounds. 

Meanwhile, San Antonio had enough points to win and then some against Boston on Wednesday, taking its matchup 129-114. The Spurs can attribute much of their success to DeMar DeRozan, who had 30 points in addition to six rebounds.

Memphis suffered a grim 145-115 defeat to San Antonio the last time the two teams met in December. The Spurs have won nine of their last 12 matchups against the Grizzlies, however Memphis will enter Friday's contest full of confidence having won four of its last five games. 

So who wins Grizzlies vs. Spurs? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to find out which side of the Spurs vs. Grizzlies spread you need to jump on Friday, all from the model that has crushed its NBA picks.