trey-lance-usatsi-49ers-cbs.jpg
USATSI

Last week, the San Francisco 49ers and Las Vegas Raiders met for a slate of joint practices. On Sunday, the two teams will battle in the final game of the Week 1 NFL preseason schedule. The matchup between San Francisco and Las Vegas marks the second game of an NFL doubleheader on Sunday. Allegiant Stadium in Las Vegas, site of the 2024 Super Bowl, will host the game.

Kickoff is at 4 p.m. ET. San Francisco is a 4-point favorite, while the over/under, or total number of points Vegas thinks will be scored, is 36 in the 49ers vs. Raiders odds. Before making any Raiders vs. 49ers picks, you need to see what SportsLine NFL expert Matt Severance has to say.

Severance is a well-connected writer and high-volume handicapper who has worked in the industry since 2005. After joining SportsLine, Severance quickly established himself as a top expert in multiple sports. In fact, he is a 13-6 on his last 19 NFL picks involving the Raiders. Anybody following him is way up.

Now, Severance has locked in on Niners vs. Raiders from every angle and locked in his picks and NFL predictions. You can visit SportsLine now to see his picks. Here are several NFL odds and trends for Raiders vs. Niners: 

  • 49ers vs. Raiders spread: 49ers -4
  • 49ers vs. Raiders over/under: 36 points
  • 49ers vs. Raiders money line: 49ers -180, Raiders +150
  • San Francisco: The 49ers were 13-7 against the spread last season
  • Las Vegas: The Raiders were 8-9 against the spread last season
  • 49ers vs. Raiders picks: See picks at SportsLine

Why the 49ers can cover

San Francisco had a strong preseason in 2022, winning two of three games. While a lot of attention will be paid to the quarterback spot, there is also a battle at running back between talented players. Christian McCaffrey is not expected to play a major role in the preseason-opener and, with Elijah Mitchell out with injury, there are reps available for Tyrion Davis-Price and Jordan Mason

Davis-Price, a 2022 third round pick from LSU, earned 34 carries as a rookie and generated more than 1,000 yards in his final collegiate season. Mason appeared in all 16 games in 2022 and averaged 6.0 yards per carry during his rookie season. The 24-year-old from Georgia Tech is also a quality special teams option, and the Niners do have two prominent quarterbacks to take snaps in the opener. Trey Lance and Sam Darnold are both former No. 3 overall picks with immense talent, and each will compete for regular season playing time alongside projected starter Brock Purdy. See which team to back here.

Why the Raiders can cover

Las Vegas has a bevy of young players expected to see prominent roles in the preseason opener. That begins with 2022 fourth-round pick Zamir White, the backup running back to Josh Jacobs, who continues a holdout. White accumulated more than 2,000 yards as a five-star prospect at the college level with the Georgia Bulldogs and has a clear path to regular season playing time.

The Raiders also added a pair of intriguing rookie pass-catchers in the 2023 NFL Draft. Michael Mayer is an elite tight end prospect with more than 2,000 yards and 18 touchdowns at Notre Dame and is ready-made to contribute. Third round pick Tre Tucker arrives from Cincinnati and was highly productive at the college level. Even with first round pick Tyree Wilson sidelined with a foot injury, Las Vegas has young talent, and that also includes backup quarterback Aidan O'Connell, who is in line for snaps on Sunday. See which team to pick here.

How to make Raiders vs. 49ers picks

Severance has analyzed this matchup and while we can tell you he's leaning Over the point total, he has also discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing what it is, and which side to back, at SportsLine.

Who wins 49ers vs. Raiders, and which critical X-factor makes one side of the spread a must-back? Visit SportsLine now to see which side of the Raiders vs. 49ers spread you need to jump on, all from the red-hot expert on a 13-6 roll on Raiders picks, and find out.