Week 2 of the 2022 NFL schedule will begin with a divisional rivalry as the Los Angeles Chargers visit the Kansas City Chiefs on Thursday Night Football. Both teams emerged from their openers victorious and fans will be in for a treat with Patrick Mahomes and Justin Herbert on the field. Despite Mahomes' gaudy accomplishments, the two are often spoken about in the same breath and both will be highly sought-after for NFL player props and Chiefs vs. Chargers NFL prop bets.

Caesars Sportsbook has the over/under for Herbert's passing touchdowns at 1.5, while Mahomes' bar for passing TDs is 2.5. Each quarterback's Week 1 performance suggests they would both go over, but Herbert will be without wide receiver Keenan Allen (hamstring), while Mahomes has averaged just 2.3 passing TDs versus L.A. over his career. Which Thursday Night Football NFL props carry the most value? Before making any NFL prop bets for Chargers vs. Chiefs, you need to see the Thursday Night Football prop predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up more than $7,500 for $100 players on top-rated NFL picks since its inception. The model enters Week 2 of the 2022 NFL season on an incredible 139-98 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

It can also be used to crush NFL prop picks. Last season, its NFL prop bets went 41-29 from Week 7 on, returning over $800.

With Chiefs vs. Chargers on Thursday, the model has evaluated the NFL player props from Caesars and found five strong bets. You can only see them here.

Top NFL player prop bets for Chargers vs. Chiefs

After simulating Chiefs vs. Chargers 10,000 times, the model predicts that Chiefs quarterback Patrick Mahomes goes under 305.5 passing yards. Mahomes has gone under 305.5 yards in six of his seven career games versus the Chargers, averaging just 261 against L.A.

The Chargers had the 30th-ranked run defense last year versus the 12th-ranked pass defense. Andy Reid and his staff were well aware of that and emphasized running the ball to attack Los Angeles' biggest weakness. In the offseason, the Chargers added Pro Bowlers in edge-rusher Khalil Mack and cornerback J.C. Jackson which only adds to their strength of pass defense. Mack had three sacks in Week 1, and the best way to neutralize him is by running the ball instead of passing, which is why the model predicts Mahomes to toss for just 274 yards. See other NFL props here.

How to make NFL player prop bets for Chargers vs. Chiefs

In addition, the model says another star surpasses his yardage total and has another plus-money prop payout you'll want to jump on. You need to see the model's analysis before making any Chiefs vs. Chargers prop bets for Thursday Night Football.

Which Chargers vs. Chiefs prop bets should you target for Thursday Night Football? And which plus-money prop is a must-back? Visit SportsLine now to see the top Chiefs vs. Chargers props, all from the model that's up over $7,500 on top-rated NFL picks.