Josh Allen and Stefon Diggs are one of the league's most dynamic duos and so it's inevitable that in a single-game slate they're a popular option for NFL DFS stacks. The Buffalo Bills will host the Denver Broncos on Monday Night Football in Week 10 and Denver's 31st-ranked scoring defense will look alluring to anybody looking to plug Allen and Diggs into their NFL DFS lineups. However, the Broncos have only allowed 15.0 points per game over their last three contests and held the Chiefs to just 274 yards of total offense in their last outing.

Denver is also coming off a bye week and that extra prep time might allow head coach Sean Payton to unlock the potential in his offense. How much exposure should you have to Russell Wilson, Jerry Jeudy and Courtland Sutton, and who else in the NFL DFS player pool might be of value in this primetime matchup? Before locking in any NFL DFS picks for Bills vs. Broncos on sites like DraftKings and FanDuel, be sure to check out the NFL DFS advice, strategy, and stacks from SportsLine daily Fantasy expert Mike McClure.

McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends, and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings.

He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1% in more than a dozen other tournaments. Last year, he won the DraftKings Millionaire Maker twice and the FanDuel Million once.

Now, McClure has turned his attention to Bills vs. Broncos on Monday Night Football and locked in his top daily Fantasy football picks. You can only see them by heading to SportsLine.

Top NFL DFS picks for Bills vs. Broncos

One of McClure's top NFL DFS picks for Monday Night Football is Bills tight end Dalton Kincaid. Despite Dawson Knox producing 1,104 receiving yards and 15 touchdowns over the last two seasons, the Bills spent a first-round pick to bring Kincaid into the fold. The Utah product started his rookie season somewhat sluggish but he's been heavily involved over the last three weeks.

Kincaid has been targeted 26 times during that span and has hauled in 23 receptions for 221 yards and a touchdown. He's had at least five catches for 65 yards in each of those three contests and now he'll take on a Denver defense that has struggled covering tight ends. Travis Kelce has 15 catches for 182 yards in two games against the Broncos and they also surrendered strong outings to Cole Kmet (7-85-2) and Tyler Conklin (4-67).

Part of McClure's optimal NFL DFS strategy also includes rostering Broncos running back Javonte Williams. The third-year back out of North Carolina is coming off his best game of the season against Kansas City with 98 scrimmage yards and his first touchdown of the season. 

Williams has put up 194 scrimmage yards over his last two games and has upside against a Buffalo run defense that ranks 30th in the NFL in yards allowed per carry (4.9). The Bills have allowed three running backs (Travis Etienne, De'Von Achane and Breece Hall) to crack the 100-yard mark this season and Williams could have a big day on Monday if Denver can keep it close. See the rest of McClure's NFL DFS player pool right here.  

How to set NFL DFS lineups for Broncos vs. Bills

McClure is also targeting an undervalued player who is set to explode for huge numbers on Monday Night Football. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is here. 

So who is Mike McClure putting in his optimal NFL DFS lineups for Monday Night Football? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from a daily Fantasy expert with more than $2 million in winnings, and find out.