Aaron Rodgers and the Green Bay Packers face a substantial challenge in Week 16. Green Bay enters its Sunday Night Football matchup with an 11-3 record to lead the NFC, but the Packers square off against a potent team in the Tennessee Titans. The Titans, led by Derrick Henry, are 10-4 overall and 5-1 away from home this season. Tennessee also has stellar quarterback play from Ryan Tannehill, and the Titans will look to match Green Bay's firepower with an explosive offense of their own. 

Kickoff from Lambeau Field is set for 8:20 p.m. ET. William Hill Sportsbook lists Green Bay as a three-point home favorite, and the total number of points Vegas thinks will be scored, or the over-under, is 53 in the latest Packers vs. Titans odds. Before you lock in your Titans vs. Packers picks, see the latest Sunday Night Football predictions from SportsLine's proven projection model. 

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception five-plus years ago. It is a sizzling 22-11 on top-rated NFL picks this season, returning more than $800. The model also enters Week 15 on an incredible 118-76 run on top-rated NFL picks that dates back to the 2017 season.

The model ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up. 

Now, the model has set its sights on Titans vs. Packers. You can visit SportsLine now to see the picks. Here are the NFL odds and trends for Packers vs. Titans:

  • Packers vs. Titans spread: Packers -3
  • Packers vs. Titans over-under: 53 points
  • Packers vs. Titans money line: Packers -175, Titans +155
  • TEN: Titans are 5-2 against the spread in the last seven games
  • GB: Packers are 9-5 against the spread this season

Why the Titans can cover

The offense gets the attention for the Titans with good reason, but Tennessee does deploy some high-end talent defensively and this is an opportunistic group. The Titans are a top-10 team in the NFL with 13 interceptions, displaying aggressiveness to the ball, and Malcolm Butler ranks in the top-10 of the league with 13 passes defended. Butler is also in the top-10 of the entire league in solo tackles (75), and the Titans are above-average in limiting the opposition's running game on a per-play basis, yielding only 4.3 yards per carry. 

With an offense that ranks in the top two of the league in scoring (30.1 points per game), total offense (399.4 yards per game) and rushing offense (160.4 yards per game), Tennessee packs quite an overall punch. 

The Titans have also had a ton of success against Green Bay in their most recent meetings. In fact, Tennessee is 4-1 in its last five matchups against the Packers. 

Why the Packers can cover

With a top-10 defense and a strong offensive line, the Packers have strengths that go well beyond their high-end skill position players offensively. At the same time, Green Bay is elite as an overall offense, and Rodgers is perhaps the biggest reason. Rodgers leads the NFL in passing touchdowns (40), passer rating (118.0), interception rate (0.8 percent) and QBR (83.6), with top-six marks in yards per attempt (8.0), completion rate (69.6 percent) and sack rate (3.64 percent). By any measure, he is one of the best players in the sport, and Rodgers has a connection with a tremendous wide receiver in Davante Adams. 

Adams leads the league in receiving yards per game (98.8) and he lands in the top seven of the NFL in receiving touchdowns (14), receptions (98) and receiving yards (1,186) this season. On the ground, Aaron Jones is tremendously effective and efficient, ranking in the top four of the NFL in rushing yards (968), rushing yards per game (80.7) and yards per carry (5.4).

How to make Packers vs. Titans picks

SportsLine's model is leaning under on the total. In fact, it's calling for 51 total points. It also says one side of the spread cashes in well over 50 percent of simulations. You can only get the pick here.

So who wins Titans vs. Packers on Sunday Night Football? And which side of the spread hits well over 50 percent of the time? Visit SportsLine now to see which side of the Titans vs. Packers spread to jump on, all from the advanced model that is up almost $7,900 on its top-rated NFL picks, and find out.