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The Tampa Bay Buccaneers (8-7) and New Orleans Saints (7-8) are only separated by a game in the NFC South standings, and the two teams will go head-to-head in Week 17. The Buccaneers could clinch the division with a win and a Falcons loss to the Bears, and Tampa Bay has both a four-game winning streak and a 26-9 win over New Orleans to anchor its confidence. However, the Saints do rank ninth in the NFL in point differential and are inside the top half of the league in both scoring, points allowed, total offense and total defense.

Kickoff is scheduled for 1 p.m. ET at Raymond James Stadium in Tampa, Fla., where the Bucs have won their last three games. The latest Buccaneers vs. Saints odds via the SportsLine consensus lists the over/under at 42.5 while Tampa Bay is the 2.5-point favorite at home. Before making any Saints vs. Buccaneers picks, you'll want to see the NFL predictions and betting advice from the proven computer simulation model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 17 of the 2023 NFL season on an incredible 178-129 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 32-21 roll on top-rated NFL picks since Week 7 of last season. 

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

The model has set its sights on Saints vs. Bucs and just locked in its picks and NFL predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and betting lines for the game:

  • Buccaneers vs. Saints spread: Buccaneers -2.5
  • Buccaneers vs. Saints over/under: 42.5 points
  • Buccaneers vs. Saints money line: Buccaneers -142, Saints +120
  • Buccaneers vs. Saints picks: See picks here
  • Buccaneers vs. Saints live stream: fubo (try for free)

What to know about the Saints

Last Thursday, the Saints came up short against the Los Angeles Rams, falling 30-22. New Orleans was down 27-7 at the end of the third quarter, which was just too much to recover from. Derek Carr put forth a good effort for the losing side as he threw for 319 yards and three touchdowns.

Carr has battled inconsistencies for the Saints in 2023, but is coming off back-to-back strong performances. For the season, the former Fresno State standout has 3,417 passing yards, 19 touchdowns passes and eight interceptions. His top target has been second year wide receiver Chris Olave, who has 81 catches for 1,041 yards and four TDs. See which team to pick here.

What to know about the Buccaneers

With Tom Brady retiring once again this offseason, Tampa Bay found itself in a bit of a quarterback bind and decided to go the economical route by signing Baker Mayfield to an incentive-laden deal. Now, the former No. 1 overall pick finds himself in the NFL Comeback Player of the Year conversation as he's put together one of his best seasons as a professional.

Mayfield has a career-high 96.2 quarterback rating and has completed 64.3% of his passes for 3,598 yards and 26 touchdowns with only eight interceptions. He's accounted for nine total touchdowns while throwing for 708 yards over his last three games and had a three-touchdown game against the Saints during a 26-9 win on Oct. 1. See which team to pick here.

How to make Buccaneers vs. Saints picks

The model has simulated Saints vs. Buccaneers 10,000 times and the results are in. The model is leaning Under on the point total, and it's also generated a point-spread pick that hits in well over 50% of simulations. You can only see the model's pick at SportsLine.

So who wins Buccaneers vs. Saints in Week 17, and which side of the spread hits in well over 50% of computer simulations? Visit SportsLine now to see which side of the spread to back, all from the model on a 178-129 roll on top-rated NFL picks, and find out.