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Minnesota was without star wide receiver Justin Jefferson (hamstring) for the first time since he was placed on the injured reserve when it faced Chicago last week. The Vikings escaped with a 19-13 win as 3-point favorites despite struggling offensively. Tight end T.J. Hockenson had a team-high 50 receiving yards, with several Minnesota wide receivers going Under their NFL props. Hockenson and teammate Jordan Addison both have totals of 48.5 receiving yards for their game against San Francisco on Monday Night Football, according to the latest NFL player props.

The Vikings will face a 49ers defense that is near the top of the league, making this a tricky matchup. Which side of Minnesota's NFL prop bets should you back wuth your MNF prop bets? Before betting any NFL props for Monday Night Football in Week 7 or entering selections on sites like PrizePicks, you need to see the Vikings vs. 49ers NFL prop predictions powered by SportsLine AI.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each player prop. The AI predictions are determined by statistically learning from each player's historical data and then quantitatively evaluating the strength of the opponents defense by assigning a numeric value out of 100 called a matchup score. 

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see a 5-star rating on an over bet if a player is facing a poor defense, their prediction differs from the line and there are favorable odds.

In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes with the most recent available data and can help you spot the biggest discrepancies in the lines. So far this season, SportsLine AI has hit a whopping 284 4.5- and 5-star prop picks for a strong profit of $452 for $100 players.

For 49ers vs. Vikings on Monday Night Football, the model has evaluated the NFL player prop odds and provided Vikings vs. 49ers prop picks for every available prop market. You can only see the AI player prop predictions for Minnesota vs. San Francisco here.

Top NFL player prop bets for Vikings vs. 49ers

After analyzing 49ers vs. Vikings and examining the dozens of NFL player prop markets, SportsLine AI says Vikings quarterback Kirk Cousins goes over 232.5 passing yards. Cousins had his second-lowest passing yardage total of the season last week, finishing with 181 yards on 31 attempts. However, he went over 280 passing yards in four of his first five games this season.

Cousins threw at least 44 passes in all four of those games, so passing volume is critical for Minnesota's signal-caller. He is facing a San Francisco team that has been scoring at will for most of the season, which means Cousins will be tasked with putting up big numbers on Monday Night Football. Game flow is a pivotal part of identifying value in prop markets, and SportsLine AI says this is a spot where the game flow benefits Cousins.

Cousins finishes with more than 300 passing yards in the latest simulations, which makes the Over a strong bet with a 4.5-star rating. See more NFL props here.

How to make NFL player prop bets for Minnesota vs. San Francisco

In addition, SportsLine AI says Cousins sails past another prop total for a plus-money payout and has seven other NFL props rated four stars or better. You need to see the model's analysis before making any 49ers vs. Vikings prop bets for Monday Night Football.

Which Vikings vs. 49ers prop bets should you target for Monday Night Football? Visit SportsLine now to see the top 49ers vs. Vikings props, all from the brand-new SportsLine AI that has nailed 284 top-rated picks this season.