The seven-game Week 0 college football schedule begins on Saturday afternoon when No. 13 Notre Dame faces Navy in Dublin at 2:30 p.m. ET. Notre Dame is a 20.5-point favorite in the Week 0 college football odds, marking one of four double-digit favorites in the Week 0 college football spreads. No. 6 USC is a 30-point favorite against San Jose State at 8 p.m. ET as it tries to begin a College Football Playoff run. Should you back either of those heavy favorites with your Week 0 college football bets?
Saturday's nightcap features a meeting between Louisiana Tech (-12) and FIU on CBS Sports Network. There is action throughout the day on Saturday, including a matchup between San Diego State (-2.5) and Ohio in the Week 0 college football lines. Before locking in any college football picks for Week 0 of the 2023 season, be sure to see the latest college football predictions from SportsLine's proven model.
The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.
Now, it has turned its attention to the latest college football odds for Week 0 and locked in picks for every FBS matchup. Head here to see every pick.
Top college football predictions for Week 0
One of the top college football picks the model is recommending for Saturday, Aug. 26: San Diego State (-2.5) cruises to a double-digit win at home against Ohio at 7 p.m. ET. The Aztecs return quarterback Jalen Mayden, who transformed the offense when he stepped in during the middle of last season. Mayden was once a quarterback recruit for Mississippi State before playing defensive back at San Diego State, responding with 2,030 passing yards and 12 touchdowns when he took over as the quarterback last year.
Mayden has a deep-threat target in Mekhi Shaw, and the Aztecs added wide receiver Raphael Williams from Western Carolina. San Diego State also has an elite defense that has not finished worse than No. 21 in the country in total defense in 10 years. Ohio will have trouble going on the road and pulling off an upset against an elite defense in Week 0 -- the model has the Aztecs covering the spread in more than 70% of simulations. See which other teams the model likes here.
How to make college football picks for Saturday, Aug. 26
The model has also made the call on who wins and covers in every other FBS matchup on Saturday, and it's calling for several teams to win in blowout fashion. You can only get every pick for every game at SportsLine.
So what college football picks can you make with confidence, and which teams win in blowout fashion? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $2,500 in profit over the past seven seasons, and find out.
College football odds for Saturday, Aug. 26
See full Week 0 college football picks, odds, predictions here
Saturday, Aug. 26
Navy vs. Notre Dame (-20.5, 49)
UTEP at Jacksonville State (+2, 54.5)
UMass at New Mexico State (-7, 45)
Ohio at San Diego State (-2.5, 48)
Hawaii at Vanderbilt (-17.5, 56)
San Jose State at USC (-31, 66)
FIU at Louisiana Tech (-12, 57.5)
