The 15th-ranked Notre Dame Fighting Irish could encounter a tricky test when they visit Death Valley on Saturday to face the Clemson Tigers in a college football Week 10 matchup. The Irish (7-2) have lost to two ranked teams but come in off consecutive victories. The Tigers (4-4, 2-4 ACC) have lost two in a row but pushed No. 4 Florida State to overtime earlier in the season. These teams faced off in the 2018 Cotton Bowl national semifinal, as well as the 2020 ACC title game. Clemson won both games, but the Irish beat the Tigers 35-14 in South Bend last year.
Saturday's kickoff is set for noon ET at Memorial Stadium in Clemson, S.C. The latest SportsLine consensus Notre Dame vs. Clemson odds list the Irish as 3.5-point favorites, according to the SportsLine consensus, and the over/under for total points scored is set at 43.5. Before making any Clemson vs. Notre Dame picks, be sure to check out the college football predictions and betting advice from SportsLine's proven computer model.
The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.
Now, the model has set its sights on Clemson vs. Notre Dame and just revealed its picks and predictions. You can visit SportsLine to see the model's CFB picks. Here are several college football odds and trends for Notre Dame vs. Clemson:
- Notre Dame vs. Clemson spread: Irish -3.5
- Notre Dame vs. Clemson over/under: 43.5 points
- Notre Dame vs. Clemson money line: Irish -175, Tigers +148
- ND: Is 5-2 ATS in its past seven road games.
- CLEM: Is 4-7 ATS at home since last season.
- Notre Dame vs. Clemson picks: See picks at SportsLine
- Notre Dame vs. Clemson live stream: fubo (try for free)
Why Notre Dame can cover
The Irish are led by veteran quarterback Sam Hartman and a defense that can make big plays. Hartman has 2,126 passing yards and 18 TD passes for an offense that averages 38.3 points (12th in FBS) and 7.0 yards per play (10th). Running back Audric Estime leads a rushing attack that averages 4.9 yards per carry, and he has 901 rushing yards and 12 touchdowns. Wide receiver Chris Tyree, who has 417 yards and averages 21.9 per catch, also is a playmaker.
The Notre Dame defense gives up just 279 yards and 15.3 points per game, both top 15 in the nation. The unit ranks third against the pass (159 yards) and has 18 takeaways and 19 sacks. Safety Xavier Watts leads the nation with six interceptions. The Irish lost to Ohio State and Louisville but beat ranked Duke and USC teams over a brutal four-game stretch, Then they throttled Pittsburgh 58-7 last Saturday, piling up 535 yards on offense and forcing five turnovers. See which team to pick here.
Why Clemson can cover
The Tigers still have one of the nation's best defenses, a unit that allows 4.3 yards per play (eighth in FBS) and 3.1 per rush (16th). Opponents are averaging 267 total yards, sixth-fewest in FBS, and 21 points (39th). T.J. Parker leads the team with four sacks, and Xavier Thomas, who has two in six games, is a force when he's on the field. Linebacker Jeremiah Trotter Jr. has 1.5 sacks, one interception and two forced fumbles, while leading the team with 54 tackles.
Clemson is waiting to see if running back Will Shipley can return from a concussion, but Phil Mafah is also a playmaker. Shipley has 635 total yards and five touchdowns, but Mafah is averaging 6 yards per carry, rushing for 439 and six TDs. Cade Klubnik can manage the game at quarterback and has plenty of weapons. Klubnik has 1,947 passing yards and 13 TDs, and five Tigers have at least 20 receptions. Beaux Collins is averaging 16.2 yards on 30 catches. See which team to pick here.
How to make Notre Dame vs. Clemson picks
SportsLine's model is leaning Over on the point total, and it also says one side of the spread hits in well over 50% of simulations. You can only see the model's pick at SportsLine.
So who wins Clemson vs. Notre Dame, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has notched a profit of well over $2,000 on its top-rated college football spread picks, and find out.
