Barry Odom and the Missouri Tigers opened up their 2019 season with extremely high hopes of competing in the SEC East after welcoming transfer quarterback Kelly Bryant into the program. Bryant threw for 423 yards in his first start for the Tigers, but he was a erratic at times, throwing an interception and fumbling on the way to a 37-31 loss at Wyoming. Now, Bryant makes his home debut on Saturday against West Virginia, and the Tigers are 13.5-point favorites with the total at 61.5 in the latest West Virginia vs. Missouri odds. Kickoff is scheduled for noon ET at Memorial Stadium. Before you make your West Virginia vs. Missouri picks, be sure to check out the college football predictions from the proven projection model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times, and those who have followed it have seen massive returns. Over the past four years, this proprietary computer model has generated a jaw-dropping $4,530 profit for $100 bettors on its top-rated spread picks. The model enters Week 2 of the 2019 college football season on a blistering 52-31 run on all top-rated picks. It also called Auburn (-3.5) covering against Oregon and Alabama (-34) covering a nearly five-touchdown spread against Duke in Week 1. Anybody who has been following it is way up.

Now, it has simulated Missouri vs. West Virginia 10,000 times and the results are in. We can tell you that the model is leaning under, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You can only see the pick at SportsLine.

The model knows that the Mountaineers will be relying on their defense on Saturday in Columbia. West Virginia allowed just 328 yards of offense and allowed first downs on just 5-of-14 third-down conversion attempts by James Madison in a 20-13 victory in Week 1.

Offensively, quarterback Austin Kendall may not have lit the world on fire, but he took care of the football (no interceptions) and threw for 260 yards and two touchdowns while completing 64.3 percent of his passes. The former Oklahoma quarterback should give first-year head coach Neal Brown some dependability to build an offense around as he takes over for Dana Holgorsen.

Meanwhile, Missouri is in a great position to bounce back from its Week 1 loss at Wyoming because the Tigers have an impressive group of skill players. Bryant has top NFL prospect Albert Okwuegbunam at tight end, as well as Larry Rountree III, a 1,200-yard rusher last year, at running back. Senior receiver Johnathon Johnson caught seven passes in Week 1, and he's closing in on becoming the school's all-time leading receiver. 

So who wins Missouri vs. West Virginia? And which side of the spread is hitting in almost 60 percent of simulations? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks